Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses

Src family kinases Fyn and Lyn are constitutively activated and mediate plasmacytoid dendritic cell responses

Type I interferon responses are a core immunoregulatory function of plasmacytoid dendritic cells (pDCs). Here the authors show that SFK family members, including Lyn and Fyn, control type I interferon production in human and mouse pDCs.

Bibliographic Details
Main Authors: S. Dallari, M. Macal, M. E. Loureiro, Y. Jo, L. Swanson, C. Hesser, P. Ghosh, E. I. Zuniga
Format: Article
Language:English
Published: Nature Portfolio 2017-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14830

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