A case of synchronous double cancers consisting of maxillary gingival carcinoma and intraductal papillary mucinous carcinoma, invasive: case report
Abstract Background The development of synchronous multiple primary cancers is one of the major causes of death in patients with head and neck cancer. Herein, we report a case of synchronous intraductal papillary mucinous carcinoma (IPMC), invasive in a patient with maxillary gingival carcinoma. Cas...
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| Format: | Article |
| Language: | English |
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BMC
2023-08-01
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| Series: | BMC Oral Health |
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| Online Access: | https://doi.org/10.1186/s12903-023-03253-y |
| _version_ | 1797451243349606400 |
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| author | Ryosuke Iwama Hitoshi Miyashita Atsumu Koketsu Kiyoshi Kume Fumiyoshi Fujishima Atsushi Masamune Tetsu Takahashi |
| author_facet | Ryosuke Iwama Hitoshi Miyashita Atsumu Koketsu Kiyoshi Kume Fumiyoshi Fujishima Atsushi Masamune Tetsu Takahashi |
| author_sort | Ryosuke Iwama |
| collection | DOAJ |
| description | Abstract Background The development of synchronous multiple primary cancers is one of the major causes of death in patients with head and neck cancer. Herein, we report a case of synchronous intraductal papillary mucinous carcinoma (IPMC), invasive in a patient with maxillary gingival carcinoma. Case presentation A 73-year-old female visited our hospital complaining of a mass on the left side of the maxillary gingiva. Intraorally, an exophytic tumor, 50 × 25 mm in size, was found on the gingiva of the left maxillary posterior, and a diagnosis of squamous cell carcinoma was revealed by cytology. Emission tomography/ computed tomography with 18 Fluorodeoxyglucose-Positron (18FDG- PET/ CT) showed increased accumulation in the left maxillary gingiva, the left side of cervical lymph nodes, and the main pancreatic duct. The pancreatic ductal tumor was performed the biopsy at esophagogastroduodenoscopy (EGD) and resulted in a pathological diagnosis of IPMC, invasive. The patient was diagnosed as synchronous double primary cancers consisting of maxillary gingival carcinoma cT4aN2bM0 and IPMC, invasive cT3N0M0. She refused radical treatment, and died 11 months later. Conclusion 18FDG- PET/ CT, EGD and multidisciplinary approach is required for the detection and determining the treatment strategy of synchronous double primary cancers. |
| first_indexed | 2024-03-09T14:51:54Z |
| format | Article |
| id | doaj.art-0b200bf096ce4931a798c478f6e470c8 |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-03-09T14:51:54Z |
| publishDate | 2023-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-0b200bf096ce4931a798c478f6e470c82023-11-26T14:25:06ZengBMCBMC Oral Health1472-68312023-08-012311610.1186/s12903-023-03253-yA case of synchronous double cancers consisting of maxillary gingival carcinoma and intraductal papillary mucinous carcinoma, invasive: case reportRyosuke Iwama0Hitoshi Miyashita1Atsumu Koketsu2Kiyoshi Kume3Fumiyoshi Fujishima4Atsushi Masamune5Tetsu Takahashi6Division of Oral and Maxillofacial Surgery, Tohoku University Graduate School of DentistryDivision of Oral and Maxillofacial Surgery, Tohoku University Graduate School of DentistryDivision of Oral and Maxillofacial Surgery, Tohoku University Graduate School of DentistryDivision of Gastroenterology, Tohoku University Graduate School of MedicineDepartment of Pathology, Tohoku University HospitalDivision of Gastroenterology, Tohoku University Graduate School of MedicineDivision of Oral and Maxillofacial Surgery, Tohoku University Graduate School of DentistryAbstract Background The development of synchronous multiple primary cancers is one of the major causes of death in patients with head and neck cancer. Herein, we report a case of synchronous intraductal papillary mucinous carcinoma (IPMC), invasive in a patient with maxillary gingival carcinoma. Case presentation A 73-year-old female visited our hospital complaining of a mass on the left side of the maxillary gingiva. Intraorally, an exophytic tumor, 50 × 25 mm in size, was found on the gingiva of the left maxillary posterior, and a diagnosis of squamous cell carcinoma was revealed by cytology. Emission tomography/ computed tomography with 18 Fluorodeoxyglucose-Positron (18FDG- PET/ CT) showed increased accumulation in the left maxillary gingiva, the left side of cervical lymph nodes, and the main pancreatic duct. The pancreatic ductal tumor was performed the biopsy at esophagogastroduodenoscopy (EGD) and resulted in a pathological diagnosis of IPMC, invasive. The patient was diagnosed as synchronous double primary cancers consisting of maxillary gingival carcinoma cT4aN2bM0 and IPMC, invasive cT3N0M0. She refused radical treatment, and died 11 months later. Conclusion 18FDG- PET/ CT, EGD and multidisciplinary approach is required for the detection and determining the treatment strategy of synchronous double primary cancers.https://doi.org/10.1186/s12903-023-03253-ySynchronous double cancersMaxillary gingival carcinomaIntraductal papillary mucinous neoplasm |
| spellingShingle | Ryosuke Iwama Hitoshi Miyashita Atsumu Koketsu Kiyoshi Kume Fumiyoshi Fujishima Atsushi Masamune Tetsu Takahashi A case of synchronous double cancers consisting of maxillary gingival carcinoma and intraductal papillary mucinous carcinoma, invasive: case report BMC Oral Health Synchronous double cancers Maxillary gingival carcinoma Intraductal papillary mucinous neoplasm |
| title | A case of synchronous double cancers consisting of maxillary gingival carcinoma and intraductal papillary mucinous carcinoma, invasive: case report |
| title_full | A case of synchronous double cancers consisting of maxillary gingival carcinoma and intraductal papillary mucinous carcinoma, invasive: case report |
| title_fullStr | A case of synchronous double cancers consisting of maxillary gingival carcinoma and intraductal papillary mucinous carcinoma, invasive: case report |
| title_full_unstemmed | A case of synchronous double cancers consisting of maxillary gingival carcinoma and intraductal papillary mucinous carcinoma, invasive: case report |
| title_short | A case of synchronous double cancers consisting of maxillary gingival carcinoma and intraductal papillary mucinous carcinoma, invasive: case report |
| title_sort | case of synchronous double cancers consisting of maxillary gingival carcinoma and intraductal papillary mucinous carcinoma invasive case report |
| topic | Synchronous double cancers Maxillary gingival carcinoma Intraductal papillary mucinous neoplasm |
| url | https://doi.org/10.1186/s12903-023-03253-y |
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