Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain

Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain

<p>Abstract</p> <p>Background</p> <p>The C-terminal domain (CTD) of HIV-1 capsid (CA), like full-length CA, forms dimers in solution and CTD dimerization is a major driving force in Gag assembly and maturation. Mutations of the residues at the CTD dimer interface impair...

Full description

Bibliographic Details
Main Authors: Cowburn David, Cooper Alan, Waheed Abdul A, Bhattacharya Shibani, Zhang Xihui, Curreli Francesca, Zhang Hongtao, Freed Eric O, Debnath Asim K
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/8/1/28

Similar Items

Similar Items