Search for Tissue Equivalent Materials Based on Exposure and Energy Absorption Buildup Factor Computations

Tissue equivalent materials (TEM) are frequently used in research as a means to determine the delivered dose to patients undergoing various therapeutic procedures. They are used in routine quality assurance and quality control procedures in diagnostic and therapeutic physics. However, very few mater...

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Main Authors: Omrane Kadri, Abdulrahman Alfuraih
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/12/2/798
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author Omrane Kadri
Abdulrahman Alfuraih
author_facet Omrane Kadri
Abdulrahman Alfuraih
author_sort Omrane Kadri
collection DOAJ
description Tissue equivalent materials (TEM) are frequently used in research as a means to determine the delivered dose to patients undergoing various therapeutic procedures. They are used in routine quality assurance and quality control procedures in diagnostic and therapeutic physics. However, very few materials that are tissue equivalent have been developed for use in research at the low photon energies involved in diagnosis radiology. The objective of this study is to describe a series of TEMs designed to radiographically imitate human tissue at diagnostic photon energies. TEMs for adipose, cortical bone, fat, lung, and muscle tissues were investigated in terms of energy absorption and exposure buildup factors for photon energy range 15–150 keV and for penetration depths up to 40 mean free path. BUF was computed based on GP-fitting method. Moreover, we also compared some radiological properties, including the total attenuation and the energy-absorption attenuation, the effective atomic number, and the CT number at 30, 100, and 120 kVp. We found that SB3, Glycerol trioleate, and MS15 perfectly mimic cortical bone, fat, and muscle tissues, respectively. Additionally, AP6 and Stracey latex are good TEM for adipose and lung tissues, respectively. The results of this work should be useful in radiation diagnosis and dosimetry applications for the large physician researcher community.
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spelling doaj.art-0b244486f8e2410caf2fcf26825270222023-11-23T12:52:55ZengMDPI AGApplied Sciences2076-34172022-01-0112279810.3390/app12020798Search for Tissue Equivalent Materials Based on Exposure and Energy Absorption Buildup Factor ComputationsOmrane Kadri0Abdulrahman Alfuraih1Department of Radiological Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh 11433, Saudi ArabiaDepartment of Radiological Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh 11433, Saudi ArabiaTissue equivalent materials (TEM) are frequently used in research as a means to determine the delivered dose to patients undergoing various therapeutic procedures. They are used in routine quality assurance and quality control procedures in diagnostic and therapeutic physics. However, very few materials that are tissue equivalent have been developed for use in research at the low photon energies involved in diagnosis radiology. The objective of this study is to describe a series of TEMs designed to radiographically imitate human tissue at diagnostic photon energies. TEMs for adipose, cortical bone, fat, lung, and muscle tissues were investigated in terms of energy absorption and exposure buildup factors for photon energy range 15–150 keV and for penetration depths up to 40 mean free path. BUF was computed based on GP-fitting method. Moreover, we also compared some radiological properties, including the total attenuation and the energy-absorption attenuation, the effective atomic number, and the CT number at 30, 100, and 120 kVp. We found that SB3, Glycerol trioleate, and MS15 perfectly mimic cortical bone, fat, and muscle tissues, respectively. Additionally, AP6 and Stracey latex are good TEM for adipose and lung tissues, respectively. The results of this work should be useful in radiation diagnosis and dosimetry applications for the large physician researcher community.https://www.mdpi.com/2076-3417/12/2/798buildup factortissue equivalent materialGP-fitting method
spellingShingle Omrane Kadri
Abdulrahman Alfuraih
Search for Tissue Equivalent Materials Based on Exposure and Energy Absorption Buildup Factor Computations
Applied Sciences
buildup factor
tissue equivalent material
GP-fitting method
title Search for Tissue Equivalent Materials Based on Exposure and Energy Absorption Buildup Factor Computations
title_full Search for Tissue Equivalent Materials Based on Exposure and Energy Absorption Buildup Factor Computations
title_fullStr Search for Tissue Equivalent Materials Based on Exposure and Energy Absorption Buildup Factor Computations
title_full_unstemmed Search for Tissue Equivalent Materials Based on Exposure and Energy Absorption Buildup Factor Computations
title_short Search for Tissue Equivalent Materials Based on Exposure and Energy Absorption Buildup Factor Computations
title_sort search for tissue equivalent materials based on exposure and energy absorption buildup factor computations
topic buildup factor
tissue equivalent material
GP-fitting method
url https://www.mdpi.com/2076-3417/12/2/798
work_keys_str_mv AT omranekadri searchfortissueequivalentmaterialsbasedonexposureandenergyabsorptionbuildupfactorcomputations
AT abdulrahmanalfuraih searchfortissueequivalentmaterialsbasedonexposureandenergyabsorptionbuildupfactorcomputations