Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation
Types of nanozymes can produce free radicals and/or reactive oxygen species (ROS) to serve as broad spectrum antibacterial materials. Developing nanozyme-based antibacterial materials with good biocompatibility exhibits promising application prospects. In this study, we doped Mo to ZIF-8 (both compo...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Chemistry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2022.1093073/full |
| _version_ | 1811305184786120704 |
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| author | Zheng Lian Zheng Lian Chunqing Lu Jiangqi Zhu Jiangqi Zhu Xining Zhang Ting Wu Youlin Xiong Zhiyi Sun Rong Yang |
| author_facet | Zheng Lian Zheng Lian Chunqing Lu Jiangqi Zhu Jiangqi Zhu Xining Zhang Ting Wu Youlin Xiong Zhiyi Sun Rong Yang |
| author_sort | Zheng Lian |
| collection | DOAJ |
| description | Types of nanozymes can produce free radicals and/or reactive oxygen species (ROS) to serve as broad spectrum antibacterial materials. Developing nanozyme-based antibacterial materials with good biocompatibility exhibits promising application prospects. In this study, we doped Mo to ZIF-8 (both components have good biocompatibility) to prepare a new nanozyme, Mo@ZIF-8, which can produce hydroxyl radicals (•OH) triggered by a low dosage of hydrogen peroxide (H2O2), exhibiting effective antibacterial capability against both Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). This work provides a reference for the design of antibacterial nanozymes with good biocompatibility. |
| first_indexed | 2024-04-13T08:20:52Z |
| format | Article |
| id | doaj.art-0b24e471e609463bb2eca4df164da665 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-13T08:20:52Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-0b24e471e609463bb2eca4df164da6652022-12-22T02:54:38ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462022-11-011010.3389/fchem.2022.10930731093073Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluationZheng Lian0Zheng Lian1Chunqing Lu2Jiangqi Zhu3Jiangqi Zhu4Xining Zhang5Ting Wu6Youlin Xiong7Zhiyi Sun8Rong Yang9School of Criminal Investigation, People’s Public Security University of China, Beijing, ChinaCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Center of Materials Science and Optoelectronics Engineering, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, ChinaSchool of Criminal Investigation, People’s Public Security University of China, Beijing, ChinaSchool of Criminal Investigation, People’s Public Security University of China, Beijing, ChinaInstitute of Evidence Law and Forensic Science, China University of Politic Science and Law, Beijing, ChinaCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Center of Materials Science and Optoelectronics Engineering, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, ChinaCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Center of Materials Science and Optoelectronics Engineering, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, ChinaCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Center of Materials Science and Optoelectronics Engineering, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, ChinaSchool of Criminal Investigation, People’s Public Security University of China, Beijing, ChinaCAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Center of Materials Science and Optoelectronics Engineering, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, ChinaTypes of nanozymes can produce free radicals and/or reactive oxygen species (ROS) to serve as broad spectrum antibacterial materials. Developing nanozyme-based antibacterial materials with good biocompatibility exhibits promising application prospects. In this study, we doped Mo to ZIF-8 (both components have good biocompatibility) to prepare a new nanozyme, Mo@ZIF-8, which can produce hydroxyl radicals (•OH) triggered by a low dosage of hydrogen peroxide (H2O2), exhibiting effective antibacterial capability against both Gram-negative bacteria (Escherichia coli) and Gram-positive bacteria (Staphylococcus aureus). This work provides a reference for the design of antibacterial nanozymes with good biocompatibility.https://www.frontiersin.org/articles/10.3389/fchem.2022.1093073/fullperoxidase-like nanozymemetal organic frameworkZIF-8molybdenumantibacterial therapy |
| spellingShingle | Zheng Lian Zheng Lian Chunqing Lu Jiangqi Zhu Jiangqi Zhu Xining Zhang Ting Wu Youlin Xiong Zhiyi Sun Rong Yang Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation Frontiers in Chemistry peroxidase-like nanozyme metal organic framework ZIF-8 molybdenum antibacterial therapy |
| title | Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation |
| title_full | Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation |
| title_fullStr | Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation |
| title_full_unstemmed | Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation |
| title_short | Mo@ZIF-8 nanozyme preparation and its antibacterial property evaluation |
| title_sort | mo zif 8 nanozyme preparation and its antibacterial property evaluation |
| topic | peroxidase-like nanozyme metal organic framework ZIF-8 molybdenum antibacterial therapy |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2022.1093073/full |
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