Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-8-(4-chlorophenyl)-4-cyano-6-hydroxy-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}-N-(4-chlorophenyl)acetamide

Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-8-(4-chlorophenyl)-4-cyano-6-hydroxy-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}-N-(4-chlorophenyl)acetamide

In the title molecule, C28H25Cl2N3O3S, the heterocyclic portion of the tetrahydroisoquinoline unit is planar while the cyclohexene ring adopts a twist-boat conformation. The two 4-chlorophenyl groups extend away from one side of this unit while the hydroxyl and acetyl groups extend away from the opp...

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Bibliographic Details
Main Authors: Mehmet Akkurt, Islam S. Marae, Joel T. Mague, Shaaban K. Mohamed, Etify A. Bakhite, Safiyyah A. H. Al-Waleedy
Format: Article
Language:English
Published: International Union of Crystallography 2021-05-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
crystal structure
tetrahydroisoquinoline
hydrogen bond
twist-boat conformation
hirshfeld surface analysis
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2056989021003674

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