A Case Report of Loperamide-Induced Ventricular Storm
Loperamide is an easily accessible antidiarrheal medication. Unlike other medications in its class, loperamide is unique in that it causes euphoria at supratherapeutic levels due to its effect on opioid receptors. Unfortunately, with its growing abuse potential also comes increasing reports of cardi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2021-01-01
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| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/2324709621990768 |
| _version_ | 1818675649584300032 |
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| author | Jerome De Vera DO Hyungjin Ben Kim DO Antoine E. Sakr MD |
| author_facet | Jerome De Vera DO Hyungjin Ben Kim DO Antoine E. Sakr MD |
| author_sort | Jerome De Vera DO |
| collection | DOAJ |
| description | Loperamide is an easily accessible antidiarrheal medication. Unlike other medications in its class, loperamide is unique in that it causes euphoria at supratherapeutic levels due to its effect on opioid receptors. Unfortunately, with its growing abuse potential also comes increasing reports of cardiotoxicity including prolonged QT, torsades de pointes, and sudden cardiac death. We report a case of a 29-year-old female who presented with unstable arrhythmia that further progressed into electrical storm in the setting of loperamide toxicity. Due to its growing popularity and availability, it is important for clinicians to understand loperamide’s mechanisms for causing toxicity as well as how to appropriately treat its complications. |
| first_indexed | 2024-12-17T08:30:56Z |
| format | Article |
| id | doaj.art-0b28b3b07ee74c5c82ff9ab3903ed870 |
| institution | Directory Open Access Journal |
| issn | 2324-7096 |
| language | English |
| last_indexed | 2024-12-17T08:30:56Z |
| publishDate | 2021-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj.art-0b28b3b07ee74c5c82ff9ab3903ed8702022-12-21T21:56:37ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962021-01-01910.1177/2324709621990768A Case Report of Loperamide-Induced Ventricular StormJerome De Vera DO0Hyungjin Ben Kim DO1Antoine E. Sakr MD2Loma Linda University Medical Center, Loma Linda, CA, USALoma Linda University Medical Center, Loma Linda, CA, USALoma Linda University Medical Center, Loma Linda, CA, USALoperamide is an easily accessible antidiarrheal medication. Unlike other medications in its class, loperamide is unique in that it causes euphoria at supratherapeutic levels due to its effect on opioid receptors. Unfortunately, with its growing abuse potential also comes increasing reports of cardiotoxicity including prolonged QT, torsades de pointes, and sudden cardiac death. We report a case of a 29-year-old female who presented with unstable arrhythmia that further progressed into electrical storm in the setting of loperamide toxicity. Due to its growing popularity and availability, it is important for clinicians to understand loperamide’s mechanisms for causing toxicity as well as how to appropriately treat its complications.https://doi.org/10.1177/2324709621990768 |
| spellingShingle | Jerome De Vera DO Hyungjin Ben Kim DO Antoine E. Sakr MD A Case Report of Loperamide-Induced Ventricular Storm Journal of Investigative Medicine High Impact Case Reports |
| title | A Case Report of Loperamide-Induced Ventricular Storm |
| title_full | A Case Report of Loperamide-Induced Ventricular Storm |
| title_fullStr | A Case Report of Loperamide-Induced Ventricular Storm |
| title_full_unstemmed | A Case Report of Loperamide-Induced Ventricular Storm |
| title_short | A Case Report of Loperamide-Induced Ventricular Storm |
| title_sort | case report of loperamide induced ventricular storm |
| url | https://doi.org/10.1177/2324709621990768 |
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