| Summary: | The basics and uses of the micellar system extraction technique (MSE) for extracting and preconcentrating nanoparticles and bioactive compounds (medicines and vitamins) are covered in this review. Hence, the influential factors of the MSE and applications are offered. The MSE, like any separation process, extracts the analytes in a small phase from the solution to improve analysis quality and remove sample background interference. The MSE has several advantages over other preconcentration and separation methods, such as speed, cheapness, security, selectivity, and safety. The use of toxic organic solvents is reduced or ignored, and the process is economical and environmentally friendly. In the latest works of literature, three different procedures use to extract nanomaterials. So bioactive molecules were separated by two methods with MSE, and this review also provided newly-developed MSE.
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