The Relationship Between Plasma DPP4 Activity to BDNF Ratio and Mild Cognitive Impairment in Elderly Population With Normal Glucose Tolerance

The Relationship Between Plasma DPP4 Activity to BDNF Ratio and Mild Cognitive Impairment in Elderly Population With Normal Glucose Tolerance

Objective: Since decreased brain-derived neurotrophic factor (BDNF) and increased dipeptidyl peptidase-4 (DPP4) activity have both been implicated in the pathogenesis of mild cognitive impairment (MCI), the aim of our study was to evaluate the association of MCI with plasma DPP4 activity to BDNF rat...

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Bibliographic Details
Main Authors: Liuping Xiao, Bo Ge, Xu Chen, Bo Chen, Linyuan Qin, Xueping Hu, Haidong Pan, Yujie Chen, Li Tian, Yun Gao, Tianpeng Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
mild cognitive impairment
DPP4 activity to BDNF ratio
oxidative stress
inflammation
normal glucose tolerance
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00033/full

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