Layer-Specific Damage Modeling of Porcine Large Intestine under Biaxial Tension
The mechanical behavior of the large intestine beyond the ultimate stress has never been investigated. Stretching beyond the ultimate stress may drastically impair the tissue microstructure, which consequently weakens its healthy state functions of absorption, temporary storage, and transportation f...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/9/10/528 |
| _version_ | 1827651568356294656 |
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| author | Aroj Bhattarai Charlotte Anabell May Manfred Staat Wojciech Kowalczyk Thanh Ngoc Tran |
| author_facet | Aroj Bhattarai Charlotte Anabell May Manfred Staat Wojciech Kowalczyk Thanh Ngoc Tran |
| author_sort | Aroj Bhattarai |
| collection | DOAJ |
| description | The mechanical behavior of the large intestine beyond the ultimate stress has never been investigated. Stretching beyond the ultimate stress may drastically impair the tissue microstructure, which consequently weakens its healthy state functions of absorption, temporary storage, and transportation for defecation. Due to closely similar microstructure and function with humans, biaxial tensile experiments on the porcine large intestine have been performed in this study. In this paper, we report hyperelastic characterization of the large intestine based on experiments in 102 specimens. We also report the theoretical analysis of the experimental results, including an exponential damage evolution function. The fracture energies and the threshold stresses are set as damage material parameters for the longitudinal muscular, the circumferential muscular and the submucosal collagenous layers. A biaxial tensile simulation of a linear brick element has been performed to validate the applicability of the estimated material parameters. The model successfully simulates the biomechanical response of the large intestine under physiological and non-physiological loads. |
| first_indexed | 2024-03-09T20:41:28Z |
| format | Article |
| id | doaj.art-0b322e2f215b4e9ab510d2845c4244e3 |
| institution | Directory Open Access Journal |
| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-09T20:41:28Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Bioengineering |
| spelling | doaj.art-0b322e2f215b4e9ab510d2845c4244e32023-11-23T22:57:22ZengMDPI AGBioengineering2306-53542022-10-0191052810.3390/bioengineering9100528Layer-Specific Damage Modeling of Porcine Large Intestine under Biaxial TensionAroj Bhattarai0Charlotte Anabell May1Manfred Staat2Wojciech Kowalczyk3Thanh Ngoc Tran4Department of Orthopaedic Surgery, University of Saarland, 66424 Homburg, GermanyInstitute of Bioengineering, FH Aachen University of Applied Sciences, 52428 Jülich, GermanyInstitute of Bioengineering, FH Aachen University of Applied Sciences, 52428 Jülich, GermanyChair of Mechanics and Robotics, University of Duisburg-Essen, 47057 Duisburg, GermanyDepartment of Orthopaedic Surgery, University of Saarland, 66424 Homburg, GermanyThe mechanical behavior of the large intestine beyond the ultimate stress has never been investigated. Stretching beyond the ultimate stress may drastically impair the tissue microstructure, which consequently weakens its healthy state functions of absorption, temporary storage, and transportation for defecation. Due to closely similar microstructure and function with humans, biaxial tensile experiments on the porcine large intestine have been performed in this study. In this paper, we report hyperelastic characterization of the large intestine based on experiments in 102 specimens. We also report the theoretical analysis of the experimental results, including an exponential damage evolution function. The fracture energies and the threshold stresses are set as damage material parameters for the longitudinal muscular, the circumferential muscular and the submucosal collagenous layers. A biaxial tensile simulation of a linear brick element has been performed to validate the applicability of the estimated material parameters. The model successfully simulates the biomechanical response of the large intestine under physiological and non-physiological loads.https://www.mdpi.com/2306-5354/9/10/528biaxial tensile experimentanisotropyhyperelasticconstitutive modelingdamage |
| spellingShingle | Aroj Bhattarai Charlotte Anabell May Manfred Staat Wojciech Kowalczyk Thanh Ngoc Tran Layer-Specific Damage Modeling of Porcine Large Intestine under Biaxial Tension Bioengineering biaxial tensile experiment anisotropy hyperelastic constitutive modeling damage |
| title | Layer-Specific Damage Modeling of Porcine Large Intestine under Biaxial Tension |
| title_full | Layer-Specific Damage Modeling of Porcine Large Intestine under Biaxial Tension |
| title_fullStr | Layer-Specific Damage Modeling of Porcine Large Intestine under Biaxial Tension |
| title_full_unstemmed | Layer-Specific Damage Modeling of Porcine Large Intestine under Biaxial Tension |
| title_short | Layer-Specific Damage Modeling of Porcine Large Intestine under Biaxial Tension |
| title_sort | layer specific damage modeling of porcine large intestine under biaxial tension |
| topic | biaxial tensile experiment anisotropy hyperelastic constitutive modeling damage |
| url | https://www.mdpi.com/2306-5354/9/10/528 |
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