Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia
BackgroundCongenital heart disease (CHD) patients are thought to be vulnerable to COVID-19 complications. In this study, we would like to assess the outcomes and clinical characteristics in COVID-19 CHD patients.MethodA single-center, observational study was conducted in National Cardiovascular Cent...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-11-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1022183/full |
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| author | Sisca Natalia Siagian Susandy Oetama Fathy Zuandi Pohan Brian Mendel Brian Mendel Olfi Lelya Damba Dwisepto Aulia Sakti Yovi Kurniawati |
| author_facet | Sisca Natalia Siagian Susandy Oetama Fathy Zuandi Pohan Brian Mendel Brian Mendel Olfi Lelya Damba Dwisepto Aulia Sakti Yovi Kurniawati |
| author_sort | Sisca Natalia Siagian |
| collection | DOAJ |
| description | BackgroundCongenital heart disease (CHD) patients are thought to be vulnerable to COVID-19 complications. In this study, we would like to assess the outcomes and clinical characteristics in COVID-19 CHD patients.MethodA single-center, observational study was conducted in National Cardiovascular Center Harapan Kita (NCCHK). This study included patients with CHD who were hospitalized for COVID-19. The extracted data were baseline characteristics, clinical findings, supportive examination findings, complications, outcomes, and length of stay of the patients. The data were then analyzed using SPSS 26.0 software.ResultTwenty-six patients with CHD and COVID-19 infection were included in our study. There were 24 resolved cases and 2 deaths, four patients experienced complications such as renal insufficiency (1), sepsis (2), and multiorgan failure (1). The median length of stay was 13 days. The most common symptoms experienced by the patients were breathlessness (65.4%), cough (57.7%), and fever (42.3%).ConclusionWe observed a relatively mild COVID-19 clinical course despite prior research showing that patients with cardiovascular comorbidities, such as CHD, have a higher case-fatality rate. This could be because of the smaller sample size, non-standardized diagnosis, severity, treatment, and age group. |
| first_indexed | 2024-04-11T23:48:17Z |
| format | Article |
| id | doaj.art-0b34eefbcef342cb83c9411d9db78903 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-11T23:48:17Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-0b34eefbcef342cb83c9411d9db789032022-12-22T03:56:34ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-11-01910.3389/fcvm.2022.10221831022183Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in IndonesiaSisca Natalia Siagian0Susandy Oetama1Fathy Zuandi Pohan2Brian Mendel3Brian Mendel4Olfi Lelya5Damba Dwisepto Aulia Sakti6Yovi Kurniawati7Division of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaDivision of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaDivision of Pediatric Cardiac Intensive Care, National Cardiovascular Centre Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaDivision of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaSultan Sulaiman Government Hospital, Serdang Bedagai, IndonesiaDivision of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaDivision of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaDivision of Pediatric Cardiology and Congenital Heart Disease, Department of Cardiology and Vascular Medicine, National Cardiovascular Centre Harapan Kita, Universitas Indonesia, Jakarta, IndonesiaBackgroundCongenital heart disease (CHD) patients are thought to be vulnerable to COVID-19 complications. In this study, we would like to assess the outcomes and clinical characteristics in COVID-19 CHD patients.MethodA single-center, observational study was conducted in National Cardiovascular Center Harapan Kita (NCCHK). This study included patients with CHD who were hospitalized for COVID-19. The extracted data were baseline characteristics, clinical findings, supportive examination findings, complications, outcomes, and length of stay of the patients. The data were then analyzed using SPSS 26.0 software.ResultTwenty-six patients with CHD and COVID-19 infection were included in our study. There were 24 resolved cases and 2 deaths, four patients experienced complications such as renal insufficiency (1), sepsis (2), and multiorgan failure (1). The median length of stay was 13 days. The most common symptoms experienced by the patients were breathlessness (65.4%), cough (57.7%), and fever (42.3%).ConclusionWe observed a relatively mild COVID-19 clinical course despite prior research showing that patients with cardiovascular comorbidities, such as CHD, have a higher case-fatality rate. This could be because of the smaller sample size, non-standardized diagnosis, severity, treatment, and age group.https://www.frontiersin.org/articles/10.3389/fcvm.2022.1022183/fullclinical outcomecongenital heart diseaseCHD (congenital heart disease)COVID-19comorbidities |
| spellingShingle | Sisca Natalia Siagian Susandy Oetama Fathy Zuandi Pohan Brian Mendel Brian Mendel Olfi Lelya Damba Dwisepto Aulia Sakti Yovi Kurniawati Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia Frontiers in Cardiovascular Medicine clinical outcome congenital heart disease CHD (congenital heart disease) COVID-19 comorbidities |
| title | Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia |
| title_full | Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia |
| title_fullStr | Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia |
| title_full_unstemmed | Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia |
| title_short | Clinical outcomes of COVID-19 infection in congenital heart disease: A single-center experience in Indonesia |
| title_sort | clinical outcomes of covid 19 infection in congenital heart disease a single center experience in indonesia |
| topic | clinical outcome congenital heart disease CHD (congenital heart disease) COVID-19 comorbidities |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.1022183/full |
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