Tracking of Glycans Structure and Metallomics Profiles in <i>BRAF</i> Mutated Melanoma Cells Treated with Vemurafenib

Tracking of Glycans Structure and Metallomics Profiles in <i>BRAF</i> Mutated Melanoma Cells Treated with Vemurafenib

Nearly half of patients with advanced and metastatic melanomas harbor a <i>BRAF</i> mutation. Vemurafenib (VEM), a BRAF inhibitor, is used to treat such patients, however, responses to VEM are very short-lived due to intrinsic, adaptive and/or acquired resistance. In this context, we pre...

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Bibliographic Details
Main Authors: Monika K. Nisiewicz, Agata Kowalczyk, Anna Sobiepanek, Agata Jagielska, Barbara Wagner, Julita Nowakowska, Marianna Gniadek, Ireneusz P. Grudzinski, Tomasz Kobiela, Anna M. Nowicka
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
glycans structure
metallomics profile
melanoma cells with <i>BRAF</i> mutation
vemurafenib
<i>α</i>1-acid glycoprotein
Online Access:https://www.mdpi.com/1422-0067/22/1/439

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