Plasma Exchange as a Rescue Therapy for Acute Liver Failure
Acute Liver Failure (ALF) is a life-threatening condition and often necessitates Liver Transplantation (LT). However, LT is not available to most patients in developing countries due to resource constraints. Here, authors presents a case of 30-year-old female with ALF and fulfilled the criteria fo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2021-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/15371/49865_CE[Ra1]_F(SHU)_PF1(AKA_SH_KM)_PFA(AKA_KM)_PN(KM).pdf |
| _version_ | 1819005796680204288 |
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| author | Nupur B Patel Anand Sharma Itish Patnaik Ashok Kumar |
| author_facet | Nupur B Patel Anand Sharma Itish Patnaik Ashok Kumar |
| author_sort | Nupur B Patel |
| collection | DOAJ |
| description | Acute Liver Failure (ALF) is a life-threatening condition and often necessitates Liver Transplantation (LT). However, LT is not available
to most patients in developing countries due to resource constraints. Here, authors presents a case of 30-year-old female with ALF
and fulfilled the criteria for LT. The aetiology of ALF could not be diagnosed in her. Due to the lack of LT facilities, she was offered
plasma exchange as a therapeutic option, which resulted in improvement in sensorium and Liver Function Tests (LFT) {bilirubin,
International Normalised Ratio (INR), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT)} over a period of two
weeks. She was discharged and was doing well during follow-up. Plasma exchange is a less studied but potential treatment option
for ALF when LT is not feasible. |
| first_indexed | 2024-12-20T23:58:29Z |
| format | Article |
| id | doaj.art-0b3d7f447b5b43008054f37fe43f6a07 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-20T23:58:29Z |
| publishDate | 2021-09-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-0b3d7f447b5b43008054f37fe43f6a072022-12-21T19:22:40ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-09-01159OD07OD0910.7860/JCDR/2021/49865.15371Plasma Exchange as a Rescue Therapy for Acute Liver FailureNupur B PatelAnand Sharma Itish PatnaikAshok KumarAcute Liver Failure (ALF) is a life-threatening condition and often necessitates Liver Transplantation (LT). However, LT is not available to most patients in developing countries due to resource constraints. Here, authors presents a case of 30-year-old female with ALF and fulfilled the criteria for LT. The aetiology of ALF could not be diagnosed in her. Due to the lack of LT facilities, she was offered plasma exchange as a therapeutic option, which resulted in improvement in sensorium and Liver Function Tests (LFT) {bilirubin, International Normalised Ratio (INR), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT)} over a period of two weeks. She was discharged and was doing well during follow-up. Plasma exchange is a less studied but potential treatment option for ALF when LT is not feasible.https://www.jcdr.net/articles/PDF/15371/49865_CE[Ra1]_F(SHU)_PF1(AKA_SH_KM)_PFA(AKA_KM)_PN(KM).pdfgastroenterologyhepatitisliver function tests |
| spellingShingle | Nupur B Patel Anand Sharma Itish Patnaik Ashok Kumar Plasma Exchange as a Rescue Therapy for Acute Liver Failure Journal of Clinical and Diagnostic Research gastroenterology hepatitis liver function tests |
| title | Plasma Exchange as a Rescue Therapy for Acute Liver Failure |
| title_full | Plasma Exchange as a Rescue Therapy for Acute Liver Failure |
| title_fullStr | Plasma Exchange as a Rescue Therapy for Acute Liver Failure |
| title_full_unstemmed | Plasma Exchange as a Rescue Therapy for Acute Liver Failure |
| title_short | Plasma Exchange as a Rescue Therapy for Acute Liver Failure |
| title_sort | plasma exchange as a rescue therapy for acute liver failure |
| topic | gastroenterology hepatitis liver function tests |
| url | https://www.jcdr.net/articles/PDF/15371/49865_CE[Ra1]_F(SHU)_PF1(AKA_SH_KM)_PFA(AKA_KM)_PN(KM).pdf |
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