Features of reaction of coagulation hemostasis in children with pneumonia

The article presents data from a study of 161 child with pneumonia. Two groups of patients with uncomplicated pneumonia and pneumonia with pleural pulmonary complication were formed. The study of coagulation hemostasis was realized in the studied groups. It was found that in children with uncomplica...

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Main Authors: N. A. Dorokhov, E. V. Skudarnov, D. A. Antropov
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2016-02-01
Series:Acta Biomedica Scientifica
Subjects:
Online Access:https://www.actabiomedica.ru/jour/article/view/147
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author N. A. Dorokhov
E. V. Skudarnov
D. A. Antropov
author_facet N. A. Dorokhov
E. V. Skudarnov
D. A. Antropov
author_sort N. A. Dorokhov
collection DOAJ
description The article presents data from a study of 161 child with pneumonia. Two groups of patients with uncomplicated pneumonia and pneumonia with pleural pulmonary complication were formed. The study of coagulation hemostasis was realized in the studied groups. It was found that in children with uncomplicated pneumonia levels of SFMC and D-dimer were significantly higher than in normal conditions that indicates activation of coagulation hemostasis. When complicated by pneumonia hemostasis matches the current intravascular coagulation: thrombocytosis, increased levels of fibrinogen, hypo-or hypercoagulation on aPTT, changing TV thrombinemia (SFMC is 5 times higher than normal), and increased level of D-dimer, inhibition of fibrinolysis, which indicates more pronounced activation of coagulation in children with pneumonia.
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spelling doaj.art-0b426183141e457dacdd6a051b2fefe72024-03-28T07:49:15ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962016-02-0111121510.12737/21478147Features of reaction of coagulation hemostasis in children with pneumoniaN. A. Dorokhov0E. V. Skudarnov1D. A. Antropov2Altai State Medical UniversityAltai State Medical UniversityAltai State Medical UniversityThe article presents data from a study of 161 child with pneumonia. Two groups of patients with uncomplicated pneumonia and pneumonia with pleural pulmonary complication were formed. The study of coagulation hemostasis was realized in the studied groups. It was found that in children with uncomplicated pneumonia levels of SFMC and D-dimer were significantly higher than in normal conditions that indicates activation of coagulation hemostasis. When complicated by pneumonia hemostasis matches the current intravascular coagulation: thrombocytosis, increased levels of fibrinogen, hypo-or hypercoagulation on aPTT, changing TV thrombinemia (SFMC is 5 times higher than normal), and increased level of D-dimer, inhibition of fibrinolysis, which indicates more pronounced activation of coagulation in children with pneumonia.https://www.actabiomedica.ru/jour/article/view/147childrenpneumoniahemostasis
spellingShingle N. A. Dorokhov
E. V. Skudarnov
D. A. Antropov
Features of reaction of coagulation hemostasis in children with pneumonia
Acta Biomedica Scientifica
children
pneumonia
hemostasis
title Features of reaction of coagulation hemostasis in children with pneumonia
title_full Features of reaction of coagulation hemostasis in children with pneumonia
title_fullStr Features of reaction of coagulation hemostasis in children with pneumonia
title_full_unstemmed Features of reaction of coagulation hemostasis in children with pneumonia
title_short Features of reaction of coagulation hemostasis in children with pneumonia
title_sort features of reaction of coagulation hemostasis in children with pneumonia
topic children
pneumonia
hemostasis
url https://www.actabiomedica.ru/jour/article/view/147
work_keys_str_mv AT nadorokhov featuresofreactionofcoagulationhemostasisinchildrenwithpneumonia
AT evskudarnov featuresofreactionofcoagulationhemostasisinchildrenwithpneumonia
AT daantropov featuresofreactionofcoagulationhemostasisinchildrenwithpneumonia