HIV gp120 induces, NF-kappaB dependent, HIV replication that requires procaspase 8.

HIV gp120 induces, NF-kappaB dependent, HIV replication that requires procaspase 8.

HIV envelope glycoprotein gp120 causes cellular activation resulting in anergy, apoptosis, proinflammatory cytokine production, and through an unknown mechanism, enhanced HIV replication.We describe that the signals which promote apoptosis are also responsible for the enhanced HIV replication. Speci...

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Bibliographic Details
Main Authors:	Gary D Bren, Sergey A Trushin, Joe Whitman, Brett Shepard, Andrew D Badley
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2009-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2653723?pdf=render

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