Analysis of the Hypoxic Response in a Mouse Cortical Collecting Duct-Derived Cell Line Suggests That Esrra Is Partially Involved in Hif1α-Mediated Hypoxia-Inducible Gene Expression in mCCD<sub>cl1</sub> Cells

Analysis of the Hypoxic Response in a Mouse Cortical Collecting Duct-Derived Cell Line Suggests That Esrra Is Partially Involved in Hif1α-Mediated Hypoxia-Inducible Gene Expression in mCCD<sub>cl1</sub> Cells

The kidney is strongly dependent on a continuous oxygen supply, and is conversely highly sensitive to hypoxia. Controlled oxygen gradients are essential for renal control of solutes and urine-concentrating mechanisms, which also depend on various hormones including aldosterone. The cortical collecti...

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Bibliographic Details
Main Authors: Anna Keppner, Darko Maric, Ilaria Maria Christina Orlando, Laurent Falquet, Edith Hummler, David Hoogewijs
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
hypoxia
collecting duct
Hif
oxygen
kidney
Online Access:https://www.mdpi.com/1422-0067/23/13/7262

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