Diagnosis of Hypomagnesaemia in Heifer calves and Experimental Treatment with Magnesium Oxide and Basil &Thyme

Hypomagnesaemia was reported as a common clinical problem in calves in Egypt. The present study was conducted to diagnose hypomagnesemia in calves and evaluate the treatment of diseased cases by using Mg oxide, Basil &Thyme as food additives. Currently, a total of 1000 female Holstein dairy c...

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Main Authors: Naglaa Farage Hassan, Mahmoud Mohamed Arafa Mohamed, Al-Sagher Omran Ali, Adel El-Sayed Ahmed Mohamed
Format: Article
Language:English
Published: South Valley University 2023-12-01
Series:SVU-International Journal of Veterinary Sciences
Subjects:
Online Access:https://svu.journals.ekb.eg/article_333126.html
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author Naglaa Farage Hassan
Mahmoud Mohamed Arafa Mohamed
Al-Sagher Omran Ali
Adel El-Sayed Ahmed Mohamed
author_facet Naglaa Farage Hassan
Mahmoud Mohamed Arafa Mohamed
Al-Sagher Omran Ali
Adel El-Sayed Ahmed Mohamed
author_sort Naglaa Farage Hassan
collection DOAJ
description Hypomagnesaemia was reported as a common clinical problem in calves in Egypt. The present study was conducted to diagnose hypomagnesemia in calves and evaluate the treatment of diseased cases by using Mg oxide, Basil &Thyme as food additives. Currently, a total of 1000 female Holstein dairy calves imported from Europe to the farm of the Faculty of Agriculture- Sakha- Agriculture of Research Institute aged 7-9 months, out of these calves 450 have nervous manifestations suspected hypomagnesemia and confirmed by detection of serum magnesium. After symptomatic treatment of diseased cases, calves were separated and divided into 4 groups each one containing 50 calves; the apparently healthy group (control) fed on a balanced ration according to NRC, diseased calves fed on a ration with a high protein diet, treated calves fed on a balanced ration with the addition of Mg oxide 10gm/animal/day for 2 months and treated calves fed on balanced ration with the addition of Basil and Thyme 2% (2 kg/100 kg ration) for 2 months. According to the findings, there was a significant decrease in sodium, phosphorus, magnesium, ionized magnesium, calcium, ionized calcium, GSH, SOD, TAC, glucose, insulin, cortisol, and PTH levels while, there was an increase in potassium, liver, and kidney enzymes, CPK, T4, in diseased group comparing with the control one. Treating diseased animals with magnesium oxide or Basil and Thyme revealed improvement of minerals, antioxidants, glucose, insulin, cortisol, PTH levels, and a decrease in liver & kidney enzymes, T4, MDA, & CPK levels within normal range.
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spelling doaj.art-0b491726edce4fb5a8d1ada1ee84c2842024-03-30T12:57:32ZengSouth Valley UniversitySVU-International Journal of Veterinary Sciences2535-18262535-18772023-12-0164739210.21608/SVU.2023.228161.1290Diagnosis of Hypomagnesaemia in Heifer calves and Experimental Treatment with Magnesium Oxide and Basil &ThymeNaglaa Farage Hassan0 Mahmoud Mohamed Arafa Mohamed1Al-Sagher Omran Ali2Adel El-Sayed Ahmed Mohamed3Department of Biochemistry, Animal Health Research Institute, Agriculture Research Center, Sohag, EgyptDepartment of Biochemistry, Animal Health Research Institute, Agriculture Research Center, Dokii, Egypt.Division of Infectious Diseases, Animal Medicine Department, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt.Division of Clinical Laboratory Diagnosis, Department of Animal Medicine, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt.Hypomagnesaemia was reported as a common clinical problem in calves in Egypt. The present study was conducted to diagnose hypomagnesemia in calves and evaluate the treatment of diseased cases by using Mg oxide, Basil &Thyme as food additives. Currently, a total of 1000 female Holstein dairy calves imported from Europe to the farm of the Faculty of Agriculture- Sakha- Agriculture of Research Institute aged 7-9 months, out of these calves 450 have nervous manifestations suspected hypomagnesemia and confirmed by detection of serum magnesium. After symptomatic treatment of diseased cases, calves were separated and divided into 4 groups each one containing 50 calves; the apparently healthy group (control) fed on a balanced ration according to NRC, diseased calves fed on a ration with a high protein diet, treated calves fed on a balanced ration with the addition of Mg oxide 10gm/animal/day for 2 months and treated calves fed on balanced ration with the addition of Basil and Thyme 2% (2 kg/100 kg ration) for 2 months. According to the findings, there was a significant decrease in sodium, phosphorus, magnesium, ionized magnesium, calcium, ionized calcium, GSH, SOD, TAC, glucose, insulin, cortisol, and PTH levels while, there was an increase in potassium, liver, and kidney enzymes, CPK, T4, in diseased group comparing with the control one. Treating diseased animals with magnesium oxide or Basil and Thyme revealed improvement of minerals, antioxidants, glucose, insulin, cortisol, PTH levels, and a decrease in liver & kidney enzymes, T4, MDA, & CPK levels within normal range.https://svu.journals.ekb.eg/article_333126.htmlionized magnesiumionized calciumcpkproteinparathyroid
spellingShingle Naglaa Farage Hassan
Mahmoud Mohamed Arafa Mohamed
Al-Sagher Omran Ali
Adel El-Sayed Ahmed Mohamed
Diagnosis of Hypomagnesaemia in Heifer calves and Experimental Treatment with Magnesium Oxide and Basil &Thyme
SVU-International Journal of Veterinary Sciences
ionized magnesium
ionized calcium
cpk
protein
parathyroid
title Diagnosis of Hypomagnesaemia in Heifer calves and Experimental Treatment with Magnesium Oxide and Basil &Thyme
title_full Diagnosis of Hypomagnesaemia in Heifer calves and Experimental Treatment with Magnesium Oxide and Basil &Thyme
title_fullStr Diagnosis of Hypomagnesaemia in Heifer calves and Experimental Treatment with Magnesium Oxide and Basil &Thyme
title_full_unstemmed Diagnosis of Hypomagnesaemia in Heifer calves and Experimental Treatment with Magnesium Oxide and Basil &Thyme
title_short Diagnosis of Hypomagnesaemia in Heifer calves and Experimental Treatment with Magnesium Oxide and Basil &Thyme
title_sort diagnosis of hypomagnesaemia in heifer calves and experimental treatment with magnesium oxide and basil thyme
topic ionized magnesium
ionized calcium
cpk
protein
parathyroid
url https://svu.journals.ekb.eg/article_333126.html
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