Prodigiosin Promotes Nrf2 Activation to Inhibit Oxidative Stress Induced by Microcystin-LR in HepG2 Cells

Prodigiosin Promotes Nrf2 Activation to Inhibit Oxidative Stress Induced by Microcystin-LR in HepG2 Cells

Microcystin-LR (MC-LR), a cyanotoxin produced by cyanobacteria, induces oxidative stress in various types of cells. Prodigiosin, a red linear tripyrrole pigment, has been recently reported to have antimicrobial, antioxidative, and anticancer properties. How prodigiosin reacts to reactive oxygen spec...

Full description

Bibliographic Details
Main Authors: Jihua Chen, Yuji Li, Fuqiang Liu, De-Xing Hou, Jingjing Xu, Xinying Zhao, Fei Yang, Xiangling Feng
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Toxins
Subjects:
prodigiosin
microcystin-LR
ROS
Nrf2
ubiquitination
Online Access:https://www.mdpi.com/2072-6651/11/7/403

Similar Items

Similar Items