Bisulfite treatment and single-molecule real-time sequencing reveal D-loop length, position, and distribution

Bisulfite treatment and single-molecule real-time sequencing reveal D-loop length, position, and distribution

Displacement loops (D-loops) are signature intermediates formed during homologous recombination. Numerous factors regulate D-loop formation and disruption, thereby influencing crucial aspects of DNA repair, including donor choice and the possibility of crossover outcome. While D-loop detection metho...

Full description

Bibliographic Details
Main Authors: Shanaya Shital Shah, Stella R Hartono, Frédéric Chédin, Wolf-Dietrich Heyer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
recombination
genome stability
DNA repair
Online Access:https://elifesciences.org/articles/59111

Similar Items

Similar Items