Inflammation and blood-brain barrier breach remote from the primary injury following neurotrauma

Inflammation and blood-brain barrier breach remote from the primary injury following neurotrauma

Abstract Background Following injury to the central nervous system, increased microglia, secretion of pro- and anti-inflammatory cytokines, and altered blood-brain barrier permeability, a hallmark of degeneration, are observed at and immediately adjacent to the injury site. However, few studies inve...

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Bibliographic Details
Main Authors: Nicole M. Smith, Marcus K. Giacci, Alexander Gough, Charlotte Bailey, Terence McGonigle, Anna M. B. Black, Thomas O. Clarke, Carole A. Bartlett, K. Swaminathan Iyer, Sarah A. Dunlop, Melinda Fitzgerald
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Neuroinflammation
Subjects:
Neurotrauma
Secondary degeneration
Microglia
Macrophages
Cytokines
Blood-brain barrier
Online Access:http://link.springer.com/article/10.1186/s12974-018-1227-0

Internet

http://link.springer.com/article/10.1186/s12974-018-1227-0

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