Diagnosing Pseudoarthrosis After Anterior Cervical Discectomy and Fusion

Radiographic confirmation of fusion after anterior cervical discectomy and fusion (ACDF) surgery is a critical aspect of determining surgical success. However, there is a lack of established diagnostic radiographic parameters for pseudoarthrosis. The purpose of this study is to summarize the finding...

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Main Authors: Wenbo Lin, Alex Ha, Venkat Boddapati, Wen Yuan, K. Daniel Riew
Format: Article
Language:English
Published: Korean Spinal Neurosurgery Society 2018-09-01
Series:Neurospine
Subjects:
Online Access:http://www.e-neurospine.org/upload/pdf/ns-1836192-096.pdf
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author Wenbo Lin
Alex Ha
Venkat Boddapati
Wen Yuan
K. Daniel Riew
author_facet Wenbo Lin
Alex Ha
Venkat Boddapati
Wen Yuan
K. Daniel Riew
author_sort Wenbo Lin
collection DOAJ
description Radiographic confirmation of fusion after anterior cervical discectomy and fusion (ACDF) surgery is a critical aspect of determining surgical success. However, there is a lack of established diagnostic radiographic parameters for pseudoarthrosis. The purpose of this study is to summarize the findings of previous studies, review the advantages and disadvantages of frequently employed diagnostic criteria, and present our recommended protocol of fusion assessment. This study identified randomized controlled trials, case-control studies, and prospective and retrospective cohort studies reporting on spinal fusion and how successful fusion after ACDF. Among the 39 articles reviewed, bridging bone across the operated levels on static radiographs was the most commonly used criteria to confirm fusion (31 of 39, 79%). Dynamic flexion-extension radiographs were used to assess for interspinous movement (ISM) (22 of 39, 56.4%) and change in Cobb angle (12 of 39, 30.8%). Computed tomography (CT) based findings (21 of 39, 53.8%) were employed in ambiguous cases with improved sensitivity and specificity. Reconstructed CT scans were used to assess for intragraft bridging bone and extragraft bridging bone (ExGBB). ExGBB were proved to have the highest diagnostic sensitivity and specificity for pseudoarthrosis detection when compared to all other radiographic criteria. The ISM <1 mm on dynamic flexion-extension radiographs had high diagnostic sensitivity and specificity as well. After our reviewing, we recommend using dynamic lateral flexion-extension cervical spine radiographs at 150% magnificationin which the interspinous motion <1 mm and superjacent interspinous motion ≥4 mm confirms fusion. In ambiguous cases, we recommend using reconstructed CT scans to evaluate for ExGBB.
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spelling doaj.art-0b4b81679f704daf9388db00c2801b0f2024-02-02T20:59:26ZengKorean Spinal Neurosurgery SocietyNeurospine2586-65832586-65912018-09-0115319420510.14245/ns.1836192.096821Diagnosing Pseudoarthrosis After Anterior Cervical Discectomy and FusionWenbo Lin0Alex Ha1Venkat Boddapati2Wen Yuan3K. Daniel Riew4 Department of Orthopedic, Changzheng Hospital, Second Military Medical University, Shang Hai, China Orthopaedic Surgery, Columbia University Medical Center, The Spine Hospital, New York-Presbyterian Healthcare System, New York, NY, USA Orthopaedic Surgery, Columbia University Medical Center, The Spine Hospital, New York-Presbyterian Healthcare System, New York, NY, USA Department of Orthopedic, Changzheng Hospital, Second Military Medical University, Shang Hai, China Orthopaedic Surgery, Columbia University Medical Center, The Spine Hospital, New York-Presbyterian Healthcare System, New York, NY, USARadiographic confirmation of fusion after anterior cervical discectomy and fusion (ACDF) surgery is a critical aspect of determining surgical success. However, there is a lack of established diagnostic radiographic parameters for pseudoarthrosis. The purpose of this study is to summarize the findings of previous studies, review the advantages and disadvantages of frequently employed diagnostic criteria, and present our recommended protocol of fusion assessment. This study identified randomized controlled trials, case-control studies, and prospective and retrospective cohort studies reporting on spinal fusion and how successful fusion after ACDF. Among the 39 articles reviewed, bridging bone across the operated levels on static radiographs was the most commonly used criteria to confirm fusion (31 of 39, 79%). Dynamic flexion-extension radiographs were used to assess for interspinous movement (ISM) (22 of 39, 56.4%) and change in Cobb angle (12 of 39, 30.8%). Computed tomography (CT) based findings (21 of 39, 53.8%) were employed in ambiguous cases with improved sensitivity and specificity. Reconstructed CT scans were used to assess for intragraft bridging bone and extragraft bridging bone (ExGBB). ExGBB were proved to have the highest diagnostic sensitivity and specificity for pseudoarthrosis detection when compared to all other radiographic criteria. The ISM <1 mm on dynamic flexion-extension radiographs had high diagnostic sensitivity and specificity as well. After our reviewing, we recommend using dynamic lateral flexion-extension cervical spine radiographs at 150% magnificationin which the interspinous motion <1 mm and superjacent interspinous motion ≥4 mm confirms fusion. In ambiguous cases, we recommend using reconstructed CT scans to evaluate for ExGBB.http://www.e-neurospine.org/upload/pdf/ns-1836192-096.pdfAnterior cervical spine surgeryAnterior cervical discectomy and fusionAnterior cervical arthrodesis surgeryCervical spine fusionFusionPseudarthrosis
spellingShingle Wenbo Lin
Alex Ha
Venkat Boddapati
Wen Yuan
K. Daniel Riew
Diagnosing Pseudoarthrosis After Anterior Cervical Discectomy and Fusion
Neurospine
Anterior cervical spine surgery
Anterior cervical discectomy and fusion
Anterior cervical arthrodesis surgery
Cervical spine fusion
Fusion
Pseudarthrosis
title Diagnosing Pseudoarthrosis After Anterior Cervical Discectomy and Fusion
title_full Diagnosing Pseudoarthrosis After Anterior Cervical Discectomy and Fusion
title_fullStr Diagnosing Pseudoarthrosis After Anterior Cervical Discectomy and Fusion
title_full_unstemmed Diagnosing Pseudoarthrosis After Anterior Cervical Discectomy and Fusion
title_short Diagnosing Pseudoarthrosis After Anterior Cervical Discectomy and Fusion
title_sort diagnosing pseudoarthrosis after anterior cervical discectomy and fusion
topic Anterior cervical spine surgery
Anterior cervical discectomy and fusion
Anterior cervical arthrodesis surgery
Cervical spine fusion
Fusion
Pseudarthrosis
url http://www.e-neurospine.org/upload/pdf/ns-1836192-096.pdf
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