Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes
Palladium-catalyzed base-free addition of aryltriolborates to aldehydes has been developed, leading to a wide range of carbinol derivatives in good to excellent yields. The efficiency of this transformation was demonstrated by compatibility with a wide range of functional groups. The present synthet...
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-09-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/22/9/1580 |
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| author | Kun Hu Pengqing Ye Qianqian Zhen Xinrong Yao Tong Xu Yinlin Shao Jiuxi Chen |
| author_facet | Kun Hu Pengqing Ye Qianqian Zhen Xinrong Yao Tong Xu Yinlin Shao Jiuxi Chen |
| author_sort | Kun Hu |
| collection | DOAJ |
| description | Palladium-catalyzed base-free addition of aryltriolborates to aldehydes has been developed, leading to a wide range of carbinol derivatives in good to excellent yields. The efficiency of this transformation was demonstrated by compatibility with a wide range of functional groups. The present synthetic route to carbinol derivatives could be readily scaled up to gram quantity without difficulty. Thus, this method represents a simple and practical procedure to access carbinol derivatives. |
| first_indexed | 2024-12-10T10:28:41Z |
| format | Article |
| id | doaj.art-0b4da0c114c54fcf9367608367d66beb |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-10T10:28:41Z |
| publishDate | 2017-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-0b4da0c114c54fcf9367608367d66beb2022-12-22T01:52:39ZengMDPI AGMolecules1420-30492017-09-01229158010.3390/molecules22091580molecules22091580Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to AldehydesKun Hu0Pengqing Ye1Qianqian Zhen2Xinrong Yao3Tong Xu4Yinlin Shao5Jiuxi Chen6College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaCollege of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, ChinaPalladium-catalyzed base-free addition of aryltriolborates to aldehydes has been developed, leading to a wide range of carbinol derivatives in good to excellent yields. The efficiency of this transformation was demonstrated by compatibility with a wide range of functional groups. The present synthetic route to carbinol derivatives could be readily scaled up to gram quantity without difficulty. Thus, this method represents a simple and practical procedure to access carbinol derivatives.https://www.mdpi.com/1420-3049/22/9/1580palladium-catalyzedbase-freecarbinol derivativesaryltriolboratesaldehydes |
| spellingShingle | Kun Hu Pengqing Ye Qianqian Zhen Xinrong Yao Tong Xu Yinlin Shao Jiuxi Chen Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes Molecules palladium-catalyzed base-free carbinol derivatives aryltriolborates aldehydes |
| title | Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes |
| title_full | Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes |
| title_fullStr | Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes |
| title_full_unstemmed | Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes |
| title_short | Efficient Approach to Carbinol Derivatives through Palladium-Catalyzed Base-Free Addition of Aryltriolborates to Aldehydes |
| title_sort | efficient approach to carbinol derivatives through palladium catalyzed base free addition of aryltriolborates to aldehydes |
| topic | palladium-catalyzed base-free carbinol derivatives aryltriolborates aldehydes |
| url | https://www.mdpi.com/1420-3049/22/9/1580 |
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