Proline catabolism is a key factor facilitating Candida albicans pathogenicity.
Candida albicans, the primary etiology of human mycoses, is well-adapted to catabolize proline to obtain energy to initiate morphological switching (yeast to hyphal) and for growth. We report that put1-/- and put2-/- strains, carrying defective Proline UTilization genes, display remarkable proline s...
Main Authors: | Fitz Gerald S Silao, Tong Jiang, Biborka Bereczky-Veress, Andreas Kühbacher, Kicki Ryman, Nathalie Uwamohoro, Sabrina Jenull, Filomena Nogueira, Meliza Ward, Thomas Lion, Constantin F Urban, Steffen Rupp, Karl Kuchler, Changbin Chen, Christiane Peuckert, Per O Ljungdahl |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2023-11-01
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Series: | PLoS Pathogens |
Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011677&type=printable |
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