Several Biochemical Differences between the Production Strains, Cholera Chemical Vaccine Producers
Detected are several differences in biochemical properties of V. cholerae 569 B Inaba and V. cholerae M41 Ogawa productive strains. The differences are in the protein content in culture liquid, in the dynamics of enzyme activity in the process of reactor strain growth, and in the protease, phospholi...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
2011-06-01
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| Series: | Проблемы особо опасных инфекций |
| Subjects: | |
| Online Access: | https://journal.microbe.ru/jour/article/view/688 |
| _version_ | 1797220918171271168 |
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| author | I. A. Kuz`michenko O. V. Gromova M. N. Kireev N. I. Belyakova |
| author_facet | I. A. Kuz`michenko O. V. Gromova M. N. Kireev N. I. Belyakova |
| author_sort | I. A. Kuz`michenko |
| collection | DOAJ |
| description | Detected are several differences in biochemical properties of V. cholerae 569 B Inaba and V. cholerae M41 Ogawa productive strains. The differences are in the protein content in culture liquid, in the dynamics of enzyme activity in the process of reactor strain growth, and in the protease, phospholipase A2 and C activity. Demonstrated is the diverse resistance of enzymes of both of the strains to formaldehyde detoxification effect. Identified is the difference in enzyme activity of fractions, which are obtained by means of isoelectric precipitation of culture liquid proteins within the limits of pH 3,5-4,4. |
| first_indexed | 2024-03-08T13:44:04Z |
| format | Article |
| id | doaj.art-0b5a21d1310845a6a4ab478c5e892c0a |
| institution | Directory Open Access Journal |
| issn | 0370-1069 2658-719X |
| language | Russian |
| last_indexed | 2024-04-24T12:57:10Z |
| publishDate | 2011-06-01 |
| publisher | Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” |
| record_format | Article |
| series | Проблемы особо опасных инфекций |
| spelling | doaj.art-0b5a21d1310845a6a4ab478c5e892c0a2024-04-05T16:47:07ZrusFederal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”Проблемы особо опасных инфекций0370-10692658-719X2011-06-0103(109)788010.21055/0370-1069-2011-3(109)-78-80672Several Biochemical Differences between the Production Strains, Cholera Chemical Vaccine ProducersI. A. Kuz`michenko0O. V. Gromova1M. N. Kireev2N. I. Belyakova3Russian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeRussian Research Anti-Plague Institute MicrobeDetected are several differences in biochemical properties of V. cholerae 569 B Inaba and V. cholerae M41 Ogawa productive strains. The differences are in the protein content in culture liquid, in the dynamics of enzyme activity in the process of reactor strain growth, and in the protease, phospholipase A2 and C activity. Demonstrated is the diverse resistance of enzymes of both of the strains to formaldehyde detoxification effect. Identified is the difference in enzyme activity of fractions, which are obtained by means of isoelectric precipitation of culture liquid proteins within the limits of pH 3,5-4,4.https://journal.microbe.ru/jour/article/view/688cholera vibrioproduction strainculture liquid enzymes |
| spellingShingle | I. A. Kuz`michenko O. V. Gromova M. N. Kireev N. I. Belyakova Several Biochemical Differences between the Production Strains, Cholera Chemical Vaccine Producers Проблемы особо опасных инфекций cholera vibrio production strain culture liquid enzymes |
| title | Several Biochemical Differences between the Production Strains, Cholera Chemical Vaccine Producers |
| title_full | Several Biochemical Differences between the Production Strains, Cholera Chemical Vaccine Producers |
| title_fullStr | Several Biochemical Differences between the Production Strains, Cholera Chemical Vaccine Producers |
| title_full_unstemmed | Several Biochemical Differences between the Production Strains, Cholera Chemical Vaccine Producers |
| title_short | Several Biochemical Differences between the Production Strains, Cholera Chemical Vaccine Producers |
| title_sort | several biochemical differences between the production strains cholera chemical vaccine producers |
| topic | cholera vibrio production strain culture liquid enzymes |
| url | https://journal.microbe.ru/jour/article/view/688 |
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