The trend of antibiotic resistance of Staphylococcus aureus isolated in clinical specimens in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran (2009-2014)
Background: Staphylococcus is an important pathogen for humans, which is found on skin, mucous membranes and oropharynx of healthy individuals. The bacteria can cause a range of infections from simple wounds and skin abscesses to severe infections such as pneumonia, septicemia, osteomyelitis and end...
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| Format: | Article |
| Language: | English |
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Hormozgan University of Medical Sciences
2017-12-01
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| Series: | Disease and Diagnosis |
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| Online Access: | https://ddj.hums.ac.ir/PDF/iejm-53.pdf |
| _version_ | 1818367359656656896 |
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| author | Tahereh Khalafi Seyede Rooya Mohebbi Fatemeh Moradi Fatemeh Khanipour Ramin Mahmoudian Maryam Montaseri Tasnim eqhbal eftekhaari Afsaneh Karmostaji Maryam ansari |
| author_facet | Tahereh Khalafi Seyede Rooya Mohebbi Fatemeh Moradi Fatemeh Khanipour Ramin Mahmoudian Maryam Montaseri Tasnim eqhbal eftekhaari Afsaneh Karmostaji Maryam ansari |
| author_sort | Tahereh Khalafi |
| collection | DOAJ |
| description | Background: Staphylococcus is an important pathogen for humans, which is found on skin, mucous membranes and oropharynx of healthy individuals. The bacteria can cause a range of infections from simple wounds and skin abscesses to severe infections such as pneumonia, septicemia, osteomyelitis and endocarditis. Unfortunately because of emerging drug resistance, infections caused by this organism are difficult to treat and may be a leading cause of mortality. This study was aimed to assess the pattern and trend of resistance in Staphylococcus aureus in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran. Method: A prospective cross-sectional study was designed from 2009-2014 on 406 strains of Staphylococcus aureus isolated from patients admitted to a referral hospital in south of Iran. The samples were collected from urine, wounds, ear discharge, burn wound, throat, tracheal secretions, abscess and joint fluid. Antibiotic susceptibility pattern was tested by disc diffusion. The results were analyzed with SPSS 21, using descriptive statistics. Results: Of the collected isolates, 63% were from Men and 37% were from Women. Mean age of the patients was 35 Years. Highest resistance rate was observed for Amoxicillin (88.6%) and lowest resistance was identified for Ciprofloxacin (19.9%). Conclusion: Emerging of multidrug resistance is alarming among Staphylococcus aureus in south of Iran. The abundance of antibiotic prescription and antibiotic sensitivity pattern should be considered because The antibiotic sensitivity varies in different times and different regions. Necessary measures should be taken. appropriate patient treatment and planning should be designed to control and reduce the resistant species, morbidity and mortality associated with MRSA infections. |
| first_indexed | 2024-12-13T22:50:48Z |
| format | Article |
| id | doaj.art-0b5c512f207646f485d993d4e4be9986 |
| institution | Directory Open Access Journal |
| issn | 2717-3232 |
| language | English |
| last_indexed | 2024-12-13T22:50:48Z |
| publishDate | 2017-12-01 |
| publisher | Hormozgan University of Medical Sciences |
| record_format | Article |
| series | Disease and Diagnosis |
| spelling | doaj.art-0b5c512f207646f485d993d4e4be99862022-12-21T23:28:38ZengHormozgan University of Medical SciencesDisease and Diagnosis2717-32322017-12-01625357iejm-53The trend of antibiotic resistance of Staphylococcus aureus isolated in clinical specimens in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran (2009-2014)Tahereh Khalafi0Seyede Rooya Mohebbi1Fatemeh Moradi2Fatemeh Khanipour3Ramin Mahmoudian4Maryam Montaseri5Tasnim eqhbal eftekhaari6Afsaneh Karmostaji7Maryam ansari8Student Research Committee , Hormozgan University of Medical Sciences, Bandar Abbas, IranStudent Research Committee , Hormozgan University of Medical Sciences, Bandar Abbas, IranStudent Research Committee , Hormozgan University of Medical Sciences, Bandar Abbas, IranStudent Research Committee , Hormozgan University of Medical Sciences, Bandar Abbas, IranLaboratory science student , Hormozgan University of Medical Sciences, Bandar Abbas, IranMaster of Science in Biostatistics, Hormozgan University of Medical Sciences, Bandar Abbas, IranMolecular Medicine Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, IranInfectious Disease Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, IranMaster of Science in Genetics. Hormozgan University of Medical Sciences, Bandar Abbas, IranBackground: Staphylococcus is an important pathogen for humans, which is found on skin, mucous membranes and oropharynx of healthy individuals. The bacteria can cause a range of infections from simple wounds and skin abscesses to severe infections such as pneumonia, septicemia, osteomyelitis and endocarditis. Unfortunately because of emerging drug resistance, infections caused by this organism are difficult to treat and may be a leading cause of mortality. This study was aimed to assess the pattern and trend of resistance in Staphylococcus aureus in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran. Method: A prospective cross-sectional study was designed from 2009-2014 on 406 strains of Staphylococcus aureus isolated from patients admitted to a referral hospital in south of Iran. The samples were collected from urine, wounds, ear discharge, burn wound, throat, tracheal secretions, abscess and joint fluid. Antibiotic susceptibility pattern was tested by disc diffusion. The results were analyzed with SPSS 21, using descriptive statistics. Results: Of the collected isolates, 63% were from Men and 37% were from Women. Mean age of the patients was 35 Years. Highest resistance rate was observed for Amoxicillin (88.6%) and lowest resistance was identified for Ciprofloxacin (19.9%). Conclusion: Emerging of multidrug resistance is alarming among Staphylococcus aureus in south of Iran. The abundance of antibiotic prescription and antibiotic sensitivity pattern should be considered because The antibiotic sensitivity varies in different times and different regions. Necessary measures should be taken. appropriate patient treatment and planning should be designed to control and reduce the resistant species, morbidity and mortality associated with MRSA infections.https://ddj.hums.ac.ir/PDF/iejm-53.pdfstaphylococcus aureusresistancedisc diffusionmrsa |
| spellingShingle | Tahereh Khalafi Seyede Rooya Mohebbi Fatemeh Moradi Fatemeh Khanipour Ramin Mahmoudian Maryam Montaseri Tasnim eqhbal eftekhaari Afsaneh Karmostaji Maryam ansari The trend of antibiotic resistance of Staphylococcus aureus isolated in clinical specimens in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran (2009-2014) Disease and Diagnosis staphylococcus aureus resistance disc diffusion mrsa |
| title | The trend of antibiotic resistance of Staphylococcus aureus isolated in clinical specimens in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran (2009-2014) |
| title_full | The trend of antibiotic resistance of Staphylococcus aureus isolated in clinical specimens in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran (2009-2014) |
| title_fullStr | The trend of antibiotic resistance of Staphylococcus aureus isolated in clinical specimens in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran (2009-2014) |
| title_full_unstemmed | The trend of antibiotic resistance of Staphylococcus aureus isolated in clinical specimens in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran (2009-2014) |
| title_short | The trend of antibiotic resistance of Staphylococcus aureus isolated in clinical specimens in a referral hospital Shahid mohammadi hospital at Bandar abbas, South of Iran (2009-2014) |
| title_sort | trend of antibiotic resistance of staphylococcus aureus isolated in clinical specimens in a referral hospital shahid mohammadi hospital at bandar abbas south of iran 2009 2014 |
| topic | staphylococcus aureus resistance disc diffusion mrsa |
| url | https://ddj.hums.ac.ir/PDF/iejm-53.pdf |
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