BRCA immunohistochemistry for screening of BRCA mutation in epithelial ovarian cancer patients

BRCA immunohistochemistry for screening of BRCA mutation in epithelial ovarian cancer patients

To evaluate BRCA1/2 immunohistochemistry (IHC) as a screening test for germline BRCA1/2 in epithelial ovarian cancer (EOC), tumor tissue from 105 EOC patients who had germline BRCA mutations, including 9 BRCA1 mutations, 6 BRCA2 mutations and 90 no BRCA mutations, were studied. Paraffin-embedded tis...

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Bibliographic Details
Main Authors: Tarinee Manchana, Patou Tantbirojn, Natkrita Pohthipornthawat
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Gynecologic Oncology Reports
Subjects:
BRCA mutation
Immunohistochemistry
Ovarian cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578920300485

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