Epidemiology of 369 diseases and injuries attributable to 84 risk factors: 1990–2019 with 2040 projection

Summary: The global burden of diseases and injuries poses complex and pressing challenges. This study analyzed 369 diseases and injuries attributed to 84 risk factors globally from 1990 to 2019, projecting trends to 2040. In 2019, global risks caused 35 million deaths. Non-communicable diseases were...

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Main Authors: Kexin Zhang, Chengxia Kan, Jian Chen, Junfeng Shi, Yanhui Ma, Xiaoli Wang, Xuan Li, Weiqin Cai, Ruiyan Pan, Jingwen Zhang, Zhentao Guo, Fang Han, Ningning Hou, Xiaodong Sun
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224007296
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author Kexin Zhang
Chengxia Kan
Jian Chen
Junfeng Shi
Yanhui Ma
Xiaoli Wang
Xuan Li
Weiqin Cai
Ruiyan Pan
Jingwen Zhang
Zhentao Guo
Fang Han
Ningning Hou
Xiaodong Sun
author_facet Kexin Zhang
Chengxia Kan
Jian Chen
Junfeng Shi
Yanhui Ma
Xiaoli Wang
Xuan Li
Weiqin Cai
Ruiyan Pan
Jingwen Zhang
Zhentao Guo
Fang Han
Ningning Hou
Xiaodong Sun
author_sort Kexin Zhang
collection DOAJ
description Summary: The global burden of diseases and injuries poses complex and pressing challenges. This study analyzed 369 diseases and injuries attributed to 84 risk factors globally from 1990 to 2019, projecting trends to 2040. In 2019, global risks caused 35 million deaths. Non-communicable diseases were responsible for 8.2 million deaths, primarily from air pollution (5.5 million). Cardiovascular disease from air pollution had a high age-standardized disability-adjusted life year rate (1,073.40). Communicable, maternal, neonatal, and nutritional diseases caused 1.4 million deaths, mainly due to unsafe water and sanitation. Occupational risks resulted in 184,269 transport-related deaths. Behavioral risks caused 21.6 million deaths, with dietary factors causing 6.9 million cardiovascular deaths. Diabetes linked to sugar-sweetened beverages showed significant growth (1990–2019). Metabolic risks led to 18.6 million deaths. Projections to 2040 indicated persistent challenges, emphasizing the urgent need for targeted interventions and policies to alleviate the global burden of diseases and injuries.
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spelling doaj.art-0b7263ff7f8640ea925c4ddeac1886402024-03-28T06:38:36ZengElsevieriScience2589-00422024-04-01274109508Epidemiology of 369 diseases and injuries attributable to 84 risk factors: 1990–2019 with 2040 projectionKexin Zhang0Chengxia Kan1Jian Chen2Junfeng Shi3Yanhui Ma4Xiaoli Wang5Xuan Li6Weiqin Cai7Ruiyan Pan8Jingwen Zhang9Zhentao Guo10Fang Han11Ningning Hou12Xiaodong Sun13Department of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaDepartment of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaSchool of Basic Medical Sciences, Guilin Medical University, Guilin, ChinaDepartment of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaDepartment of Pathology, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaSchool of Medical Imaging, Weifang Medical University, Weifang, ChinaDepartment of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USASchool of Management, Weifang Medical University, Weifang, ChinaDepartment of Pharmacy, Weifang Medical University, Weifang, ChinaDepartment of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, ChinaDepartment of Nephrology, Affiliated Hospital of Shandong Second Medical University, Weifang, China; Corresponding authorDepartment of Pathology, Affiliated Hospital of Shandong Second Medical University, Weifang, China; Corresponding authorDepartment of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, China; Corresponding authorDepartment of Endocrinology and Metabolism, Clinical Research Center, Affiliated Hospital of Shandong Second Medical University, Weifang, China; Corresponding authorSummary: The global burden of diseases and injuries poses complex and pressing challenges. This study analyzed 369 diseases and injuries attributed to 84 risk factors globally from 1990 to 2019, projecting trends to 2040. In 2019, global risks caused 35 million deaths. Non-communicable diseases were responsible for 8.2 million deaths, primarily from air pollution (5.5 million). Cardiovascular disease from air pollution had a high age-standardized disability-adjusted life year rate (1,073.40). Communicable, maternal, neonatal, and nutritional diseases caused 1.4 million deaths, mainly due to unsafe water and sanitation. Occupational risks resulted in 184,269 transport-related deaths. Behavioral risks caused 21.6 million deaths, with dietary factors causing 6.9 million cardiovascular deaths. Diabetes linked to sugar-sweetened beverages showed significant growth (1990–2019). Metabolic risks led to 18.6 million deaths. Projections to 2040 indicated persistent challenges, emphasizing the urgent need for targeted interventions and policies to alleviate the global burden of diseases and injuries.http://www.sciencedirect.com/science/article/pii/S2589004224007296Health sciencesMedical specialtyPublic healthNatural sciencesEnvironmental sciencePollution
spellingShingle Kexin Zhang
Chengxia Kan
Jian Chen
Junfeng Shi
Yanhui Ma
Xiaoli Wang
Xuan Li
Weiqin Cai
Ruiyan Pan
Jingwen Zhang
Zhentao Guo
Fang Han
Ningning Hou
Xiaodong Sun
Epidemiology of 369 diseases and injuries attributable to 84 risk factors: 1990–2019 with 2040 projection
iScience
Health sciences
Medical specialty
Public health
Natural sciences
Environmental science
Pollution
title Epidemiology of 369 diseases and injuries attributable to 84 risk factors: 1990–2019 with 2040 projection
title_full Epidemiology of 369 diseases and injuries attributable to 84 risk factors: 1990–2019 with 2040 projection
title_fullStr Epidemiology of 369 diseases and injuries attributable to 84 risk factors: 1990–2019 with 2040 projection
title_full_unstemmed Epidemiology of 369 diseases and injuries attributable to 84 risk factors: 1990–2019 with 2040 projection
title_short Epidemiology of 369 diseases and injuries attributable to 84 risk factors: 1990–2019 with 2040 projection
title_sort epidemiology of 369 diseases and injuries attributable to 84 risk factors 1990 2019 with 2040 projection
topic Health sciences
Medical specialty
Public health
Natural sciences
Environmental science
Pollution
url http://www.sciencedirect.com/science/article/pii/S2589004224007296
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