Conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modelling
A lack of cross-disciplinary unanimity prevails within addiction research. Theories conceptualizing addiction through the three-stage brain disease model contest other theories that substance use disorder is of behavioural or genetic origin. The reverberations of this lack of consensus are noticeabl...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Molecular Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2023.1166852/full |
| _version_ | 1797691120101097472 |
|---|---|
| author | Megan R. Greener Sarah J. Storr |
| author_facet | Megan R. Greener Sarah J. Storr |
| author_sort | Megan R. Greener |
| collection | DOAJ |
| description | A lack of cross-disciplinary unanimity prevails within addiction research. Theories conceptualizing addiction through the three-stage brain disease model contest other theories that substance use disorder is of behavioural or genetic origin. The reverberations of this lack of consensus are noticeable throughout addiction research and within the foundations of disease modelling. The availability of methods to investigate substance use disorder are inconsistent and sometimes unrepresentative. This review discusses theories of addiction aetiology, available models for addiction research and the strengths and limitations of current practical experimental methods of study. |
| first_indexed | 2024-03-12T02:08:48Z |
| format | Article |
| id | doaj.art-0b7319f4b65543d6884303e6336d9e38 |
| institution | Directory Open Access Journal |
| issn | 1662-5099 |
| language | English |
| last_indexed | 2024-03-12T02:08:48Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Molecular Neuroscience |
| spelling | doaj.art-0b7319f4b65543d6884303e6336d9e382023-09-06T16:04:18ZengFrontiers Media S.A.Frontiers in Molecular Neuroscience1662-50992023-09-011610.3389/fnmol.2023.11668521166852Conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modellingMegan R. GreenerSarah J. StorrA lack of cross-disciplinary unanimity prevails within addiction research. Theories conceptualizing addiction through the three-stage brain disease model contest other theories that substance use disorder is of behavioural or genetic origin. The reverberations of this lack of consensus are noticeable throughout addiction research and within the foundations of disease modelling. The availability of methods to investigate substance use disorder are inconsistent and sometimes unrepresentative. This review discusses theories of addiction aetiology, available models for addiction research and the strengths and limitations of current practical experimental methods of study.https://www.frontiersin.org/articles/10.3389/fnmol.2023.1166852/fulladdictionneurobiologybehaviourgeneticsin vivoin vitro |
| spellingShingle | Megan R. Greener Sarah J. Storr Conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modelling Frontiers in Molecular Neuroscience addiction neurobiology behaviour genetics in vivo in vitro |
| title | Conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modelling |
| title_full | Conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modelling |
| title_fullStr | Conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modelling |
| title_full_unstemmed | Conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modelling |
| title_short | Conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modelling |
| title_sort | conflicting theories on addiction aetiology and the strengths and limitations of substance use disorder disease modelling |
| topic | addiction neurobiology behaviour genetics in vivo in vitro |
| url | https://www.frontiersin.org/articles/10.3389/fnmol.2023.1166852/full |
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