Selenazolinium Salts as “Small Molecule Catalysts” with High Potency against ESKAPE Bacterial Pathogens

Selenazolinium Salts as “Small Molecule Catalysts” with High Potency against ESKAPE Bacterial Pathogens

In view of the pressing need to identify new antibacterial agents able to combat multidrug-resistant bacteria, we investigated a series of fused selenazolinium derivatives (1–8) regarding their in vitro antimicrobial activities against 25 ESKAPE-pathogen strains. Ebselen was used as reference compou...

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Bibliographic Details
Main Authors: Karolina Witek, Muhammad Jawad Nasim, Markus Bischoff, Rosmarie Gaupp, Pavel Arsenyan, Jelena Vasiljeva, Małgorzata Anna Marć, Agnieszka Olejarz, Gniewomir Latacz, Katarzyna Kieć-Kononowicz, Jadwiga Handzlik, Claus Jacob
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
selenazolinium salts
ebselen
RSeS
multidrug resistance
MRSA
ESKAPE pathogens
antibacterial agents
Online Access:https://www.mdpi.com/1420-3049/22/12/2174

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