Childhood Tuberculosis: Epidemiology, Diagnosis, Treatment, and Vaccination
Despite the existence of a government-run tuberculosis (TB) control program, the current nationwide burden of TB continues to be a public health problem in Taiwan. Intense current and previous efforts into diagnostic, therapeutic, and preventive interventions have focused on TB in adults, but childh...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2013-10-01
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| Series: | Pediatrics and Neonatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S187595721300020X |
| _version_ | 1818322069088108544 |
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| author | Kuo-Sheng Tsai Hsiao-Ling Chang Shun-Tien Chien Kwo-Liang Chen Kou-Huang Chen Ming-Hsin Mai Kow-Tong Chen |
| author_facet | Kuo-Sheng Tsai Hsiao-Ling Chang Shun-Tien Chien Kwo-Liang Chen Kou-Huang Chen Ming-Hsin Mai Kow-Tong Chen |
| author_sort | Kuo-Sheng Tsai |
| collection | DOAJ |
| description | Despite the existence of a government-run tuberculosis (TB) control program, the current nationwide burden of TB continues to be a public health problem in Taiwan. Intense current and previous efforts into diagnostic, therapeutic, and preventive interventions have focused on TB in adults, but childhood TB has been relatively neglected. Children are particularly vulnerable to severe disease and death following infection, and children with latent infections become reservoirs for future transmission following disease reactivation in adulthood, thus fueling future epidemics. Additional research, understanding, and prevention of childhood TB are urgently needed. This review assesses the epidemiology, diagnosis, treatment, and relevant principles of TB vaccine development and presents efficacy data for the currently licensed vaccines. |
| first_indexed | 2024-12-13T10:50:56Z |
| format | Article |
| id | doaj.art-0b73a0f8d38c426f931b61733badfbde |
| institution | Directory Open Access Journal |
| issn | 1875-9572 |
| language | English |
| last_indexed | 2024-12-13T10:50:56Z |
| publishDate | 2013-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj.art-0b73a0f8d38c426f931b61733badfbde2022-12-21T23:49:50ZengElsevierPediatrics and Neonatology1875-95722013-10-0154529530210.1016/j.pedneo.2013.01.019Childhood Tuberculosis: Epidemiology, Diagnosis, Treatment, and VaccinationKuo-Sheng Tsai0Hsiao-Ling Chang1Shun-Tien Chien2Kwo-Liang Chen3Kou-Huang Chen4Ming-Hsin Mai5Kow-Tong Chen6Department of Pediatrics, Sin Lau Christian Hospital, Tainan, TaiwanDivision of Surveillance, Center for Disease Control, Department of Health, Taipei, TaiwanChest Hospital, Department of Health, Executive Yuan, Tainan, TaiwanDepartment of Industrial Engineering and Management, China University of Science and Technology, Taipei, TaiwanDepartment of Industrial Engineering and Management, China University of Science and Technology, Taipei, TaiwanDivision of Infectious Disease, Department of Internal Medicine, Sin Lau Christian Hospital, Tainan, TaiwanDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan, TaiwanDespite the existence of a government-run tuberculosis (TB) control program, the current nationwide burden of TB continues to be a public health problem in Taiwan. Intense current and previous efforts into diagnostic, therapeutic, and preventive interventions have focused on TB in adults, but childhood TB has been relatively neglected. Children are particularly vulnerable to severe disease and death following infection, and children with latent infections become reservoirs for future transmission following disease reactivation in adulthood, thus fueling future epidemics. Additional research, understanding, and prevention of childhood TB are urgently needed. This review assesses the epidemiology, diagnosis, treatment, and relevant principles of TB vaccine development and presents efficacy data for the currently licensed vaccines.http://www.sciencedirect.com/science/article/pii/S187595721300020XchildhoodincidenceTaiwantuberculosis |
| spellingShingle | Kuo-Sheng Tsai Hsiao-Ling Chang Shun-Tien Chien Kwo-Liang Chen Kou-Huang Chen Ming-Hsin Mai Kow-Tong Chen Childhood Tuberculosis: Epidemiology, Diagnosis, Treatment, and Vaccination Pediatrics and Neonatology childhood incidence Taiwan tuberculosis |
| title | Childhood Tuberculosis: Epidemiology, Diagnosis, Treatment, and Vaccination |
| title_full | Childhood Tuberculosis: Epidemiology, Diagnosis, Treatment, and Vaccination |
| title_fullStr | Childhood Tuberculosis: Epidemiology, Diagnosis, Treatment, and Vaccination |
| title_full_unstemmed | Childhood Tuberculosis: Epidemiology, Diagnosis, Treatment, and Vaccination |
| title_short | Childhood Tuberculosis: Epidemiology, Diagnosis, Treatment, and Vaccination |
| title_sort | childhood tuberculosis epidemiology diagnosis treatment and vaccination |
| topic | childhood incidence Taiwan tuberculosis |
| url | http://www.sciencedirect.com/science/article/pii/S187595721300020X |
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