Mettl3-mediated mRNA m6A modification controls postnatal liver development by modulating the transcription factor Hnf4a
m6A is the most abundant RNA modification of eukaryotic mRNAs and is involved in various physiological and pathological processes. Here the authors show a role for Mettl3-mediated RNA m6A modification in postnatal liver development by regulating the Hnf4a-centered transcriptional network
Bibliographic Details
| Main Authors: |
Yan Xu,
Zhuowei Zhou,
Xinmei Kang,
Lijie Pan,
Chang Liu,
Xiaoqi Liang,
Jiajie Chu,
Shuai Dong,
Yanli Li,
Qiuli Liu,
Yuetong Sun,
Shanshan Yu,
Qi Zhang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-08-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-32169-4
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