Reconstruction of Secondary Metabolic Pathway to Synthesize Novel Metabolite in Saccharopolyspora erythraea

Reconstruction of Secondary Metabolic Pathway to Synthesize Novel Metabolite in Saccharopolyspora erythraea

Natural polyketides play important roles in clinical treatment, agriculture, and animal husbandry. Compared to natural hosts, heterologous chassis (especially Actinomycetes) have many advantages in production of polyketide compounds. As a widely studied model Actinomycete, Saccharopolyspora erythrae...

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Bibliographic Details
Main Authors:	Chong-Yang Ren, Yong Liu, Wen-Ping Wei, Junbiao Dai, Bang-Ce Ye
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Series:	Frontiers in Bioengineering and Biotechnology
Subjects:	CRISPR-Cas9 Saccharopolyspora erythraea polyketide Acyl-CoA heterologous expression metabolic pathway
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2021.628569/full

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