Chimeric Newcastle Disease Virus Vectors Expressing Human IFN-γ Mediate Target Immune Responses and Enable Multifaceted Treatments

Chimeric Newcastle Disease Virus Vectors Expressing Human IFN-γ Mediate Target Immune Responses and Enable Multifaceted Treatments

The therapeutic potential of Newcastle disease virus (NDV) has been reported as both an oncolytic agent and a vaccine vector against many antigens. However, in the individuals already immunized with NDVs, second and subsequent administration does not provide substantial benefits. In this study, two...

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Bibliographic Details
Main Authors:	Rofaida Mostafa Soliman, Keisuke Nishioka, Tomo Daidoji, Osamu Noyori, Takaaki Nakaya
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Series:	Biomedicines
Subjects:	anti-tumor response chimeric virus immune response Newcastle disease virus recombinant virus vector vaccination
Online Access:	https://www.mdpi.com/2227-9059/11/2/455

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