Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entity
Primary cutaneous lymphomas are defined as lymphoid neoplasms that present themselves clinically on the skin and do not have extra-cutaneous disease, when the diagnosis is made or even after 6 months of the diagnosis. Primary cutaneous lymphomas of B-cells are less frequent than lymphomas of T-cells...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Indian Journal of Dermatology |
| Subjects: | |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2013;volume=58;issue=5;spage=366;epage=368;aulast=Gopal |
| _version_ | 1819292311081713664 |
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| author | Manoj Madakshira Gopal Ajay Malik |
| author_facet | Manoj Madakshira Gopal Ajay Malik |
| author_sort | Manoj Madakshira Gopal |
| collection | DOAJ |
| description | Primary cutaneous lymphomas are defined as lymphoid neoplasms that present themselves clinically on the skin and do not have extra-cutaneous disease, when the diagnosis is made or even after 6 months of the diagnosis. Primary cutaneous lymphomas of B-cells are less frequent than lymphomas of T-cells. Primary B-cell lymphomas have a better prognosis than secondary B-cell lymphomas. Primary B-cell cutaneous lymphomas are classified into five types according to the World Health Organization and European Organization for Research and Treatment of Cancer classification. The primary diffuse large B-cell cutaneous lymphoma - leg type corresponds to approximately 5-10% of the B-cell cutaneous lymphomas. It is predominantly seen in elderly people and has a female preponderance. Skin lesions can be single, multiple, and even grouped. A 5-year survival rate ranges from 36 to 100% of the cases. The expression of Bcl-2, presence of multiple lesions, and involvement of both the upper limbs lead to a worse prognosis. Very few cases have been described in the literature. |
| first_indexed | 2024-12-24T03:52:31Z |
| format | Article |
| id | doaj.art-0b7d8beec6674baca7107afc07ee7c80 |
| institution | Directory Open Access Journal |
| issn | 0019-5154 1998-3611 |
| language | English |
| last_indexed | 2024-12-24T03:52:31Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-0b7d8beec6674baca7107afc07ee7c802022-12-21T17:16:32ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112013-01-0158536636810.4103/0019-5154.117303Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entityManoj Madakshira GopalAjay MalikPrimary cutaneous lymphomas are defined as lymphoid neoplasms that present themselves clinically on the skin and do not have extra-cutaneous disease, when the diagnosis is made or even after 6 months of the diagnosis. Primary cutaneous lymphomas of B-cells are less frequent than lymphomas of T-cells. Primary B-cell lymphomas have a better prognosis than secondary B-cell lymphomas. Primary B-cell cutaneous lymphomas are classified into five types according to the World Health Organization and European Organization for Research and Treatment of Cancer classification. The primary diffuse large B-cell cutaneous lymphoma - leg type corresponds to approximately 5-10% of the B-cell cutaneous lymphomas. It is predominantly seen in elderly people and has a female preponderance. Skin lesions can be single, multiple, and even grouped. A 5-year survival rate ranges from 36 to 100% of the cases. The expression of Bcl-2, presence of multiple lesions, and involvement of both the upper limbs lead to a worse prognosis. Very few cases have been described in the literature.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2013;volume=58;issue=5;spage=366;epage=368;aulast=GopalCutaneousimmunohistochemistrynon-Hodgkin lymphoma |
| spellingShingle | Manoj Madakshira Gopal Ajay Malik Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entity Indian Journal of Dermatology Cutaneous immunohistochemistry non-Hodgkin lymphoma |
| title | Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entity |
| title_full | Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entity |
| title_fullStr | Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entity |
| title_full_unstemmed | Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entity |
| title_short | Primary cutaneous diffuse large B-cell lymphoma of the upper limb: A fascinating entity |
| title_sort | primary cutaneous diffuse large b cell lymphoma of the upper limb a fascinating entity |
| topic | Cutaneous immunohistochemistry non-Hodgkin lymphoma |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2013;volume=58;issue=5;spage=366;epage=368;aulast=Gopal |
| work_keys_str_mv | AT manojmadakshiragopal primarycutaneousdiffuselargebcelllymphomaoftheupperlimbafascinatingentity AT ajaymalik primarycutaneousdiffuselargebcelllymphomaoftheupperlimbafascinatingentity |