The Hyplip2 locus causes hypertriglyceridemia by decreased clearance of triglyceridess⃞

The Hyplip2 locus causes hypertriglyceridemia by decreased clearance of triglyceridess⃞

The Hyplip2 congenic mouse strain contains part of chromosome 15 from MRL/MpJ on the BALB/cJ background. Hyplip2 mice show increased plasma levels of cholesterol and predominantly triglycerides (TGs) and are susceptible to diet-induced atherosclerosis. This study aimed at elucidation of the mechanis...

Full description

Bibliographic Details
Main Authors:	Corina J.A. Moen, Aart P. Tholens, Peter J. Voshol, Willeke de Haan, Louis M. Havekes, Peter Gargalovic, Aldons J. Lusis, Ko Willems van Dȳk, Rune R. Frants, Marten H. Hofker, Patrick C.N. Rensen
Format:	Article
Language:	English
Published:	Elsevier 2007-10-01
Series:	Journal of Lipid Research
Subjects:	congenic mice lipoproteins lipoprotein lipase triglyceride hydrolysis lipoprotein clearance
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520424630

Similar Items

Hypertriglyceridemia—Causes, Significance, and Approaches to Therapy
by: Leinys S. Santos-Baez, et al.
Published: (2020-09-01)

Apolipoprotein C-I binds free fatty acids and reduces their intracellular esterification
by: Marit Westerterp, et al.
Published: (2007-07-01)

Human plasma lipoproteins /
by: Fruchart, J. C., et al.
Published: (1989)

A simplified procedure to trace triglyceride‐rich lipoprotein metabolism in vivo
by: Zhixiong Ying, et al.
Published: (2021-04-01)

HYPERTRIGLYCERIDEMIA AS A RISK FACTOR FOR CORONARY HEART DISEASE IN YOUNGER PAKISTANI POPULATION
by: Azhar Ijaz, et al.
Published: (2016-07-01)

Metabolic fate of rat and human lipoprotein apoproteins in the rat
by: Shlomo Eisenberg, et al.
Published: (1973-07-01)

Hypertriglyceridemia and atherosclerosis
by: Jia Peng, et al.
Published: (2017-12-01)

High-density lipoproteins : from basic biology to clinical aspects /
by: Fielding, Christopher J.
Published: (2007)

Selective and independent associations of phospholipid transfer protein and hepatic lipase with the LDL subfraction distribution
by: Susan J. Murdoch, et al.
Published: (2002-08-01)

Decreased Efficiency of Very-Low-Density Lipoprotein Lipolysis Is Linked to Both Hypertriglyceridemia and Hypercholesterolemia, but It Can Be Counteracted by High-Density Lipoprotein
by: Ewa Wieczorek, et al.
Published: (2021-04-01)

A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans
by: Marina Cuchel, et al.
Published: (2017-04-01)

Hypertriglyceridemia: A new paradigm
by: Johny J Kannampilly
Published: (2018-01-01)

In vivo interactions of apoA-II, apoA-I, and hepatic lipase contributing to HDL structure and antiatherogenic functions
by: Catherine C. Hedrick, et al.
Published: (2001-04-01)

The heterogeneity of lipoproteins and their role in the development of cardiovascular diseases
by: E. A. Utkina, et al.
Published: (2019-06-01)

SR-BI-mediated selective lipid uptake segregates apoA-I and apoA-II catabolism
by: Maria C. de Beer, et al.
Published: (2005-10-01)

ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency*
by: Gery Gerritsen, et al.
Published: (2008-05-01)

ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice
by: Myron E. Hinsdale, et al.
Published: (2002-09-01)

Oxidised LDL and Anti-Oxidised LDL Antibodies Are Reduced by Lipoprotein Apheresis in a Randomised Controlled Trial on Patients with Refractory Angina and Elevated Lipoprotein(a)
by: Tina Z. Khan, et al.
Published: (2021-01-01)

Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on VLDL apolipoprotein E metabolism
by: John S. Millar, et al.
Published: (2008-03-01)

Hyperlipoproteinemia in fasting ponies
by: M.D. Morris, et al.
Published: (1972-05-01)

Brown adipose tissue takes up plasma triglycerides mostly after lipolysis
by: Padmini P.S.J. Khedoe, et al.
Published: (2015-01-01)

Role of glycosylphosphatidylinositol‐anchored high‐density lipoprotein binding protein 1 in hypertriglyceridemia and diabetes
by: Naoko Kurooka, et al.
Published: (2023-10-01)

High density Lipoprotein; What to Measure: Quality or Quantity?
by: Balasubramaniam Gayathri
Published: (2011-09-01)

Acetyl-CoA carboxylase inhibitor increases LDL-apoB production rate in NASH with cirrhosis: prevention by fenofibrate
by: Mohamad Dandan, et al.
Published: (2023-03-01)

Evaluation of Staphylococcus aureus lipoproteins: Role in nutritional acquisition and pathogenicity
by: Shideh Vatani Shahmirzadi, et al.
Published: (2016-09-01)

Mechanisms mediating insulin resistance in transgenic mice overexpressing mouse apolipoprotein A-II
by: Lawrence W. Castellani, et al.
Published: (2004-12-01)

Associations between the lipid profile and the development of hypertension in young individuals – the preliminary study
by: Piotr Chruściel, et al.
Published: (2019-06-01)

Cysteamine Decreases Low‐Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low‐Density Lipoprotein Receptor–Deficient Mice
by: Feroz Ahmad, et al.
Published: (2021-09-01)

Hypertriglyceridemia promotes dysfunctions in high-density lipoprotein increasing the cardiovascular risk
by: Richard Rarison Cavalcante Meneses, et al.
Published: (2023-01-01)

Hypertriglyceridemia and cardiovascular risk: a cautionary note about metabolic confounding
by: Allan D. Sniderman, et al.
Published: (2018-01-01)

Alternations of Lipoprotein Profiles in the Plasma as Biomarkers of Huntington’s Disease
by: Kuo-Hsuan Chang, et al.
Published: (2023-01-01)

Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9
by: Holly E. Careskey, et al.
Published: (2008-02-01)

Lipids and Lipoproteins in Health and Disease: Focus on Targeting Atherosclerosis
by: Chih-Kuo Lee, et al.
Published: (2021-08-01)

The kringle IV type 2 domain variant 4925G>A causes the elusive association signal of the LPA pentanucleotide repeat
by: Rebecca Grüneis, et al.
Published: (2022-12-01)

Association of Hypertensive Retinopathy with different serum lipid parameters in patients of Essential Hypertension: A Hospital Based Study
by: Bishwa Nath Adhikari, et al.
Published: (2018-12-01)

Lipoprotein (a): truly a direct prothrombotic factor in cardiovascular disease?
by: Michael B. Boffa, et al.
Published: (2016-05-01)

Low‐Density Lipoprotein Cholesterol Corrected for Lipoprotein(a) Cholesterol, Risk Thresholds, and Cardiovascular Events
by: Peter Willeit, et al.
Published: (2020-12-01)

Atherosclerosis is enhanced by testosterone deficiency and attenuated by CETP expression in transgenic mice
by: A.C. Casquero, et al.
Published: (2006-07-01)

Acute inhibition of hepatic β-oxidation in APOE*3Leiden mice does not affect hepatic VLDL secretion or insulin sensitivity
by: Ilse Duivenvoorden, et al.
Published: (2005-05-01)

Oxidized and electronegative low-density lipoprotein as potential biomarkers of cardiovascular risk in obese adolescents
by: Maria Camila Pruper de Freitas, et al.
Published: (2018-10-01)