Natural compound targeting BDNF V66M variant: insights from in silico docking and molecular analysis

Natural compound targeting BDNF V66M variant: insights from in silico docking and molecular analysis

Abstract Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin gene family gene that encodes proteins vital for the growth, maintenance, and survival of neurons in the nervous system. The study aimed to screen natural compounds against BDNF variant (V66M), which affects memory, cognition, and m...

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Bibliographic Details
Main Authors: Azra Sakhawat, Muhammad Umer Khan, Raima Rehman, Samiullah Khan, Muhammad Adnan Shan, Alia Batool, Muhammad Arshad Javed, Qurban Ali
Format: Article
Language:English
Published: SpringerOpen 2023-11-01
Series:AMB Express
Subjects:
Brain derived neurotropic factor
Therapy
Valine
Methionine
Online Access:https://doi.org/10.1186/s13568-023-01640-w

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