Single-nucleus gene and gene set expression-based similarity network fusion identifies autism molecular subtypes

Single-nucleus gene and gene set expression-based similarity network fusion identifies autism molecular subtypes

Abstract Background Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that is highly phenotypically and genetically heterogeneous. With the accumulation of biological sequencing data, more and more studies shift to molecular subtype-first approach, from identifying molecular su...

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Bibliographic Details
Main Authors: Junjie Zhang, Guoli Ji, Xilin Gao, Jinting Guan
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Bioinformatics
Subjects:
Single-nucleus RNA-seq data
Gene set
Similarity network fusion
Autism
Molecular subtype
Online Access:https://doi.org/10.1186/s12859-023-05278-0

Internet

https://doi.org/10.1186/s12859-023-05278-0

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