The role of inflammatory theory in the pathogenesis of atrial fibrillation

Based on the data available in the literature, it is obvious that inflammation plays a significant role in the initiation, support and progression of AF. However, it is important that AF by itself is a factor provoking the development of inflammation in the atrial myocardium, which leads to the furt...

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Main Authors: K. V. Davtyan, A. A. Kalemberg, E. N. Tsareva, O. V. Blagova, M. S. Harlap
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2019-08-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/3362
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author K. V. Davtyan
A. A. Kalemberg
E. N. Tsareva
O. V. Blagova
M. S. Harlap
author_facet K. V. Davtyan
A. A. Kalemberg
E. N. Tsareva
O. V. Blagova
M. S. Harlap
author_sort K. V. Davtyan
collection DOAJ
description Based on the data available in the literature, it is obvious that inflammation plays a significant role in the initiation, support and progression of AF. However, it is important that AF by itself is a factor provoking the development of inflammation in the atrial myocardium, which leads to the further progression of the disease according to the principle of “AF produces AF.” The question of the primacy of the development and correlations of process links is still not fully understood: does inflammation leads to fibrillation or does fibrillation leads to inflammation?The authors analyzed the data of the world literature and tried to describe the main concepts of the inflammatory theory of AF and the practical aspects of its application.
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spelling doaj.art-0b8c1da6112d44ce95aa53ae8f97fcf72023-03-29T21:23:33Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202019-08-010711011410.15829/1560-4071-2019-7-110-1142699The role of inflammatory theory in the pathogenesis of atrial fibrillationK. V. Davtyan0A. A. Kalemberg1E. N. Tsareva2O. V. Blagova3M. S. Harlap4National Research Center for Preventive MedicineNational Research Center for Preventive MedicineNational Research Center for Preventive MedicineI.M. Sechenov First Moscow State Medical UniversityNational Research Center for Preventive MedicineBased on the data available in the literature, it is obvious that inflammation plays a significant role in the initiation, support and progression of AF. However, it is important that AF by itself is a factor provoking the development of inflammation in the atrial myocardium, which leads to the further progression of the disease according to the principle of “AF produces AF.” The question of the primacy of the development and correlations of process links is still not fully understood: does inflammation leads to fibrillation or does fibrillation leads to inflammation?The authors analyzed the data of the world literature and tried to describe the main concepts of the inflammatory theory of AF and the practical aspects of its application.https://russjcardiol.elpub.ru/jour/article/view/3362atrial fibrillationinflammation markersinflammationpulmonary veinsmyocardial biopsy
spellingShingle K. V. Davtyan
A. A. Kalemberg
E. N. Tsareva
O. V. Blagova
M. S. Harlap
The role of inflammatory theory in the pathogenesis of atrial fibrillation
Российский кардиологический журнал
atrial fibrillation
inflammation markers
inflammation
pulmonary veins
myocardial biopsy
title The role of inflammatory theory in the pathogenesis of atrial fibrillation
title_full The role of inflammatory theory in the pathogenesis of atrial fibrillation
title_fullStr The role of inflammatory theory in the pathogenesis of atrial fibrillation
title_full_unstemmed The role of inflammatory theory in the pathogenesis of atrial fibrillation
title_short The role of inflammatory theory in the pathogenesis of atrial fibrillation
title_sort role of inflammatory theory in the pathogenesis of atrial fibrillation
topic atrial fibrillation
inflammation markers
inflammation
pulmonary veins
myocardial biopsy
url https://russjcardiol.elpub.ru/jour/article/view/3362
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