Research Progress in Heterologous Expression, Fermentation and Application of Microbial Transglutaminase

Transglutaminase (TG) is a widely used enzyme with excellent protein cross-linking capacity. TG is commonly found in plants, animals and microorganisms, and microbial TG (mTG) is widely used in industrial production and application because of its good enzymatic properties. This paper describes the p...

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Main Author: YAN Wenhui, SUN Xinjie, XI Xiangheng, WANG Chenying, REN Xidong
Format: Article
Language:English
Published: China Food Publishing Company 2023-12-01
Series:Shipin Kexue
Subjects:
Online Access:https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-23-026.pdf
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author YAN Wenhui, SUN Xinjie, XI Xiangheng, WANG Chenying, REN Xidong
author_facet YAN Wenhui, SUN Xinjie, XI Xiangheng, WANG Chenying, REN Xidong
author_sort YAN Wenhui, SUN Xinjie, XI Xiangheng, WANG Chenying, REN Xidong
collection DOAJ
description Transglutaminase (TG) is a widely used enzyme with excellent protein cross-linking capacity. TG is commonly found in plants, animals and microorganisms, and microbial TG (mTG) is widely used in industrial production and application because of its good enzymatic properties. This paper describes the physicochemical properties and activation mechanism of mTG, and summarizes recent progress in mTG production by wild and different genetically engineered strains. Meanwhile, the application and potential of mTG in various industrial fields are reviewed. This review is expected to provide a reference and new ideas for research on the potential of mTG for industrial production and application.
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spelling doaj.art-0b8c79b177f54d4fb2d6489205ca034b2024-01-05T07:16:13ZengChina Food Publishing CompanyShipin Kexue1002-66302023-12-01442322323910.7506/spkx1002-6630-20221125-293Research Progress in Heterologous Expression, Fermentation and Application of Microbial TransglutaminaseYAN Wenhui, SUN Xinjie, XI Xiangheng, WANG Chenying, REN Xidong0(1. State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, China; 2. Shandong Provincial Key Laboratory of Microbial Engineering, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, China; 3. School of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Sciences, Jinan 250353, China)Transglutaminase (TG) is a widely used enzyme with excellent protein cross-linking capacity. TG is commonly found in plants, animals and microorganisms, and microbial TG (mTG) is widely used in industrial production and application because of its good enzymatic properties. This paper describes the physicochemical properties and activation mechanism of mTG, and summarizes recent progress in mTG production by wild and different genetically engineered strains. Meanwhile, the application and potential of mTG in various industrial fields are reviewed. This review is expected to provide a reference and new ideas for research on the potential of mTG for industrial production and application.https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-23-026.pdftransglutaminase; activation mechanism; fermentation; heterologous expression; application
spellingShingle YAN Wenhui, SUN Xinjie, XI Xiangheng, WANG Chenying, REN Xidong
Research Progress in Heterologous Expression, Fermentation and Application of Microbial Transglutaminase
Shipin Kexue
transglutaminase; activation mechanism; fermentation; heterologous expression; application
title Research Progress in Heterologous Expression, Fermentation and Application of Microbial Transglutaminase
title_full Research Progress in Heterologous Expression, Fermentation and Application of Microbial Transglutaminase
title_fullStr Research Progress in Heterologous Expression, Fermentation and Application of Microbial Transglutaminase
title_full_unstemmed Research Progress in Heterologous Expression, Fermentation and Application of Microbial Transglutaminase
title_short Research Progress in Heterologous Expression, Fermentation and Application of Microbial Transglutaminase
title_sort research progress in heterologous expression fermentation and application of microbial transglutaminase
topic transglutaminase; activation mechanism; fermentation; heterologous expression; application
url https://www.spkx.net.cn/fileup/1002-6630/PDF/2023-44-23-026.pdf
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