From Ivacaftor to Triple Combination: A Systematic Review of Efficacy and Safety of CFTR Modulators in People with Cystic Fibrosis

From Ivacaftor to Triple Combination: A Systematic Review of Efficacy and Safety of CFTR Modulators in People with Cystic Fibrosis

Over the last years <i>CFTR</i> (cystic fibrosis transmembrane conductance regulator) modulators have shown the ability to improve relevant clinical outcomes in patients with cystic fibrosis (CF). This review aims at a systematic research of the current evidence on efficacy and tolerabil...

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Bibliographic Details
Main Authors: Andrea Gramegna, Martina Contarini, Stefano Aliberti, Rosaria Casciaro, Francesco Blasi, Carlo Castellani
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
<i>CFTR</i> modulators
clinical efficacy
safety
cystic fibrosis
Online Access:https://www.mdpi.com/1422-0067/21/16/5882

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