Features of endoscope-assisted surgery of adrenocorticotropic hormone-secreting pituitary microadenomas of different topographic types

Introduction. Adrenocorticotropic hormone-secreting (ACTH-secreting) pituitary adenoma is the most frequently diagnosed pathology at the stage of microadenoma. Selective transnasal-transsphenoidal microadenomectomy is the most effective method of treatment. Materials and methods. We studi...

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Main Authors: Nikolay Guk, Olena Danevych
Format: Article
Language:English
Published: Romodanov Neurosurgery Institute 2013-04-01
Series:Ukrainian Neurosurgical Journal
Online Access:https://theunj.org/article/view/55535
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author Nikolay Guk
Olena Danevych
author_facet Nikolay Guk
Olena Danevych
author_sort Nikolay Guk
collection DOAJ
description Introduction. Adrenocorticotropic hormone-secreting (ACTH-secreting) pituitary adenoma is the most frequently diagnosed pathology at the stage of microadenoma. Selective transnasal-transsphenoidal microadenomectomy is the most effective method of treatment. Materials and methods. We studied 35 cases of ACTH-secreting pituitary microadenomas in post-op period. All 35 patients underwent transnasal-transsphenoidal microsurgical removal of microadenomas, 8 patients underwent endoscopic assisted surgery. Results. In 75% of patients we found no visible changes of sella turcica, complex anatomy of veins and topography of tumor, pseudocapsule was marginally expressed, we found primary invasion of tumor into diaphragm of sella turcica and cavernous sinus. Conclusions. In 25% of studied ACTH-secreting pituitary microadenomas cases we found no complex microsurgical anatomy of tumor. Endocsope-assisted surgery facilitates approach to the pituitary fossa, facilitates radical removal of tumor, provides proper level of safety at surgery of pituitary gland.
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spelling doaj.art-0b8f5e43accf470bb1eefbb41795ebe92024-01-27T08:08:46ZengRomodanov Neurosurgery InstituteUkrainian Neurosurgical Journal2663-90842663-90922013-04-011202510.25305/unj.55535Features of endoscope-assisted surgery of adrenocorticotropic hormone-secreting pituitary microadenomas of different topographic typesNikolay Guk0Olena Danevych1Romodanov Neurosurgery Institute, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, Ukraine Introduction. Adrenocorticotropic hormone-secreting (ACTH-secreting) pituitary adenoma is the most frequently diagnosed pathology at the stage of microadenoma. Selective transnasal-transsphenoidal microadenomectomy is the most effective method of treatment. Materials and methods. We studied 35 cases of ACTH-secreting pituitary microadenomas in post-op period. All 35 patients underwent transnasal-transsphenoidal microsurgical removal of microadenomas, 8 patients underwent endoscopic assisted surgery. Results. In 75% of patients we found no visible changes of sella turcica, complex anatomy of veins and topography of tumor, pseudocapsule was marginally expressed, we found primary invasion of tumor into diaphragm of sella turcica and cavernous sinus. Conclusions. In 25% of studied ACTH-secreting pituitary microadenomas cases we found no complex microsurgical anatomy of tumor. Endocsope-assisted surgery facilitates approach to the pituitary fossa, facilitates radical removal of tumor, provides proper level of safety at surgery of pituitary gland.https://theunj.org/article/view/55535
spellingShingle Nikolay Guk
Olena Danevych
Features of endoscope-assisted surgery of adrenocorticotropic hormone-secreting pituitary microadenomas of different topographic types
Ukrainian Neurosurgical Journal
title Features of endoscope-assisted surgery of adrenocorticotropic hormone-secreting pituitary microadenomas of different topographic types
title_full Features of endoscope-assisted surgery of adrenocorticotropic hormone-secreting pituitary microadenomas of different topographic types
title_fullStr Features of endoscope-assisted surgery of adrenocorticotropic hormone-secreting pituitary microadenomas of different topographic types
title_full_unstemmed Features of endoscope-assisted surgery of adrenocorticotropic hormone-secreting pituitary microadenomas of different topographic types
title_short Features of endoscope-assisted surgery of adrenocorticotropic hormone-secreting pituitary microadenomas of different topographic types
title_sort features of endoscope assisted surgery of adrenocorticotropic hormone secreting pituitary microadenomas of different topographic types
url https://theunj.org/article/view/55535
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AT olenadanevych featuresofendoscopeassistedsurgeryofadrenocorticotropichormonesecretingpituitarymicroadenomasofdifferenttopographictypes