| Summary: | Introduction: Ozone therapy is the application of medical ozone through minimal punctures or direct application for therapeutic purposes to improve the functioning of organs and tissues. The use of ozone therapy in children as a complementary treatment is fully validated in diseases such as: bronchial asthma, bronchitis, allergies, Down syndrome, infantile cerebral palsy, autism spectrum disorders, and COVID-19 was added to the list.
Objective: To determine the results obtained through the application of ozone therapy in pediatric patients positive for COVID-19 in 2021.
Material and Methods: A documentary study was carried out where the bibliography published in web format and available in ScieELO, articles published in the Cuban Journal of Biomedical Research, Cuban Journal of Pharmacy, Elsevier Journal, as well as the newspapers Granma, Juventud Rebelde and Overcome. The synthesis analysis method was used.
Development: The main results of studies worldwide indicate that ozone in children decreases inflammation indices and assisted breathing time, improves oxygen saturation, and renders CRP negative in shorter periods. And it could reduce mortality.
Conclusions: : Ozone therapy is capable of improving clinical and laboratory variables such as those referred to above, due to its anti-inflammatory, antiviral and immunomodulatory properties. It is undoubtedly an adjuvant or compassionate option in the management of pediatric patients positive for COVID-19.
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