Local analgesic effect of tramadol is not mediated by opioid receptors in early postoperative pain in rats

Local analgesic effect of tramadol is not mediated by opioid receptors in early postoperative pain in rats

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BACKGROUND AND OBJECTIVES: Tramadol is known as a central acting analgesic drug, used for the treatment of moderate to severe pain. Local analgesic effect has been demonstrated, in part due to local anesthetic-like effect, but other mechanisms remain unclear. The role of peripheral opioid receptors...

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Bibliographic Details
Main Authors: Angela Maria Sousa, Hazem Adel Ashmawi
Format: Article
Language:English
Published: Sociedade Brasileira de Anestesiologia 2015-06-01
Series:Revista Brasileira de Anestesiologia
Subjects:
Tramadol
Dolor en el postoperatorio
Receptores opiáceos
Ratones Wistar
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-70942015000300186&lng=en&tlng=en

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