NTRK3 mutation in secretory carcinoma of the parotid gland: A Case report
Abstract Mammary analog secretory carcinoma (MASC) is a newly described carcinoma with a molecular hallmark of ETV6‐NTRK3 fusion that promotes oncogenesis. While MASC histopathology was well‐studied in the literature, clinical behavior remains unstudied. We present a 22‐year‐old man with painless pa...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-09-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.6243 |
| _version_ | 1828385863523893248 |
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| author | Fahad AlKaabba Abdurahman Alloghbi Yazeed Deajim Mohamad W. Sukkari Mir Yousufuddin Ali Khan Ammar Sukari |
| author_facet | Fahad AlKaabba Abdurahman Alloghbi Yazeed Deajim Mohamad W. Sukkari Mir Yousufuddin Ali Khan Ammar Sukari |
| author_sort | Fahad AlKaabba |
| collection | DOAJ |
| description | Abstract Mammary analog secretory carcinoma (MASC) is a newly described carcinoma with a molecular hallmark of ETV6‐NTRK3 fusion that promotes oncogenesis. While MASC histopathology was well‐studied in the literature, clinical behavior remains unstudied. We present a 22‐year‐old man with painless parotid mass, which was diagnosed as salivary gland cancer, MASC subtype. |
| first_indexed | 2024-12-10T05:28:20Z |
| format | Article |
| id | doaj.art-0b90821baf8448a6befb2e8e64d28a0c |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-12-10T05:28:20Z |
| publishDate | 2022-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-0b90821baf8448a6befb2e8e64d28a0c2022-12-22T02:00:38ZengWileyClinical Case Reports2050-09042022-09-01109n/an/a10.1002/ccr3.6243NTRK3 mutation in secretory carcinoma of the parotid gland: A Case reportFahad AlKaabba0Abdurahman Alloghbi1Yazeed Deajim2Mohamad W. Sukkari3Mir Yousufuddin Ali Khan4Ammar Sukari5Department of Medicine University of Maryland Medical Center Baltimore MD USACollege of Medicine King Khalid University Abha Saudi ArabiaCollege of Medicine King Khalid University Abha Saudi ArabiaFaculty of Medicine University of Aleppo Aleppo SyriaDepartment of Pathology, Detroit Medical Center Wayne State University Detroit Michigan USADepartment of Oncology Karmanos Cancer Institute, Wayne State University Detroit Michigan USAAbstract Mammary analog secretory carcinoma (MASC) is a newly described carcinoma with a molecular hallmark of ETV6‐NTRK3 fusion that promotes oncogenesis. While MASC histopathology was well‐studied in the literature, clinical behavior remains unstudied. We present a 22‐year‐old man with painless parotid mass, which was diagnosed as salivary gland cancer, MASC subtype.https://doi.org/10.1002/ccr3.6243case reportmammary analog secretory carcinomasalivary gland carcinoma |
| spellingShingle | Fahad AlKaabba Abdurahman Alloghbi Yazeed Deajim Mohamad W. Sukkari Mir Yousufuddin Ali Khan Ammar Sukari NTRK3 mutation in secretory carcinoma of the parotid gland: A Case report Clinical Case Reports case report mammary analog secretory carcinoma salivary gland carcinoma |
| title | NTRK3 mutation in secretory carcinoma of the parotid gland: A Case report |
| title_full | NTRK3 mutation in secretory carcinoma of the parotid gland: A Case report |
| title_fullStr | NTRK3 mutation in secretory carcinoma of the parotid gland: A Case report |
| title_full_unstemmed | NTRK3 mutation in secretory carcinoma of the parotid gland: A Case report |
| title_short | NTRK3 mutation in secretory carcinoma of the parotid gland: A Case report |
| title_sort | ntrk3 mutation in secretory carcinoma of the parotid gland a case report |
| topic | case report mammary analog secretory carcinoma salivary gland carcinoma |
| url | https://doi.org/10.1002/ccr3.6243 |
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