Association between acute methanol poisoning and subsequent mortality: a nationwide study in Taiwan
Abstract Background Methanol poisoning (MP) often causes acute mortality and morbidities; however, the association between MP and subsequent mortality has not been well studied. Methods We conducted a nationwide population-based cohort study by identifying 621 participants with MP from the Nationwid...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-08-01
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| Series: | BMC Public Health |
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| Online Access: | http://link.springer.com/article/10.1186/s12889-018-5918-3 |
| _version_ | 1811268998642270208 |
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| author | Jui-Yuan Chung Chung-Han Ho Yi-Chen Chen Jiann-Hwa Chen Hung-Jung Lin Jhi-Joung Wang Chien-Chin Hsu Chien-Cheng Huang |
| author_facet | Jui-Yuan Chung Chung-Han Ho Yi-Chen Chen Jiann-Hwa Chen Hung-Jung Lin Jhi-Joung Wang Chien-Chin Hsu Chien-Cheng Huang |
| author_sort | Jui-Yuan Chung |
| collection | DOAJ |
| description | Abstract Background Methanol poisoning (MP) often causes acute mortality and morbidities; however, the association between MP and subsequent mortality has not been well studied. Methods We conducted a nationwide population-based cohort study by identifying 621 participants with MP from the Nationwide Poisoning Database and 6210 participants without MP from the Longitudinal Health Insurance Database 2000 by matching the index date at a 1:10 ratio between 1999 and 2012. Comparison of the mortality rate between the two cohorts was performed by following up until 2013. Results A total of 249 (40%) participants with MP and 154 (2.5%) participants without MP died during the follow-up (p < 0.001). Statistic analysis showed that participants with MP had a higher risk for mortality than did the participants without MP (adjusted hazard ratio [AHR]: 13.48; 95% confidence interval [CI]: 10.76–16.88). The risk of mortality was highest in the first 6 months after MP (AHR: 480.34; 95% CI: 117.55–1962.75). Hypertension, chronic obstructive pulmonary disease, liver disease, malignancy, drug abuse, and lower monthly income also predicted mortality. Conclusions MP was associated with increased subsequent mortality. Close follow-up for comorbidity control and socioeconomic assistance are suggested for patients with MP. |
| first_indexed | 2024-04-12T21:33:07Z |
| format | Article |
| id | doaj.art-0b91952cdcb04ff5b2caa1a6f5dbaf70 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-04-12T21:33:07Z |
| publishDate | 2018-08-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-0b91952cdcb04ff5b2caa1a6f5dbaf702022-12-22T03:15:58ZengBMCBMC Public Health1471-24582018-08-011811810.1186/s12889-018-5918-3Association between acute methanol poisoning and subsequent mortality: a nationwide study in TaiwanJui-Yuan Chung0Chung-Han Ho1Yi-Chen Chen2Jiann-Hwa Chen3Hung-Jung Lin4Jhi-Joung Wang5Chien-Chin Hsu6Chien-Cheng Huang7Department of Emergency Medicine, Cathay General HospitalDepartment of Medical Research, Chi Mei Medical CenterDepartment of Medical Research, Chi Mei Medical CenterDepartment of Emergency Medicine, Cathay General HospitalDepartment of Emergency Medicine, Chi-Mei Medical CenterDepartment of Medical Research, Chi Mei Medical CenterDepartment of Emergency Medicine, Chi-Mei Medical CenterDepartment of Emergency Medicine, Chi-Mei Medical CenterAbstract Background Methanol poisoning (MP) often causes acute mortality and morbidities; however, the association between MP and subsequent mortality has not been well studied. Methods We conducted a nationwide population-based cohort study by identifying 621 participants with MP from the Nationwide Poisoning Database and 6210 participants without MP from the Longitudinal Health Insurance Database 2000 by matching the index date at a 1:10 ratio between 1999 and 2012. Comparison of the mortality rate between the two cohorts was performed by following up until 2013. Results A total of 249 (40%) participants with MP and 154 (2.5%) participants without MP died during the follow-up (p < 0.001). Statistic analysis showed that participants with MP had a higher risk for mortality than did the participants without MP (adjusted hazard ratio [AHR]: 13.48; 95% confidence interval [CI]: 10.76–16.88). The risk of mortality was highest in the first 6 months after MP (AHR: 480.34; 95% CI: 117.55–1962.75). Hypertension, chronic obstructive pulmonary disease, liver disease, malignancy, drug abuse, and lower monthly income also predicted mortality. Conclusions MP was associated with increased subsequent mortality. Close follow-up for comorbidity control and socioeconomic assistance are suggested for patients with MP.http://link.springer.com/article/10.1186/s12889-018-5918-3MethanolPoisoningIntoxicationMortality |
| spellingShingle | Jui-Yuan Chung Chung-Han Ho Yi-Chen Chen Jiann-Hwa Chen Hung-Jung Lin Jhi-Joung Wang Chien-Chin Hsu Chien-Cheng Huang Association between acute methanol poisoning and subsequent mortality: a nationwide study in Taiwan BMC Public Health Methanol Poisoning Intoxication Mortality |
| title | Association between acute methanol poisoning and subsequent mortality: a nationwide study in Taiwan |
| title_full | Association between acute methanol poisoning and subsequent mortality: a nationwide study in Taiwan |
| title_fullStr | Association between acute methanol poisoning and subsequent mortality: a nationwide study in Taiwan |
| title_full_unstemmed | Association between acute methanol poisoning and subsequent mortality: a nationwide study in Taiwan |
| title_short | Association between acute methanol poisoning and subsequent mortality: a nationwide study in Taiwan |
| title_sort | association between acute methanol poisoning and subsequent mortality a nationwide study in taiwan |
| topic | Methanol Poisoning Intoxication Mortality |
| url | http://link.springer.com/article/10.1186/s12889-018-5918-3 |
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