Homeodomain-interacting protein kinase 2 regulates NLRP3 inflammasome activation through endoplasmic reticulum stress in septic liver injury

Homeodomain-interacting protein kinase 2 regulates NLRP3 inflammasome activation through endoplasmic reticulum stress in septic liver injury

Objective Septic liver injury is a major burden for the clinical management of sepsis. Hepatocyte cell death plays a crucial pathophysiological role in sepsis. A recent study proposed that NLRP3 inflammasome-mediated pyroptosis participates in septic liver injury. Therefore, investigating the mechan...

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Bibliographic Details
Main Authors: Lijun Cao, Min Wen, Zhiqiang Hu, Weihe Jia, Jiayan Lin, Bo Hu, Gang Wu, Shengchuang Tong, Qinglin Chen, Xingming Liu, Xuhao Weng
Format: Article
Language:English
Published: SAGE Publishing 2023-05-01
Series:Journal of International Medical Research
Online Access:https://doi.org/10.1177/03000605231173272

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