Residual antibacterial effect of calcium hydroxide combined with chlorhexidine gel as an intracanal medicament
Introduction: Bacterial elimination from the root canal system is considered as an essential factor for a successful endodontic treatment. Aims: To investigate both in vitro and in vivo efficacy of calcium hydroxide paste (CH) combined with 2% chlorhexidine gel (CHX) at various time intervals on Ent...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Indian Journal of Dental Research |
| Subjects: | |
| Online Access: | http://www.ijdr.in/article.asp?issn=0970-9290;year=2020;volume=31;issue=6;spage=846;epage=851;aulast=Al-Sabawi |
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| author | Nawal A Al-Sabawi Fatima A Mohammad Njwan F Shehab |
| author_facet | Nawal A Al-Sabawi Fatima A Mohammad Njwan F Shehab |
| author_sort | Nawal A Al-Sabawi |
| collection | DOAJ |
| description | Introduction: Bacterial elimination from the root canal system is considered as an essential factor for a successful endodontic treatment. Aims: To investigate both in vitro and in vivo efficacy of calcium hydroxide paste (CH) combined with 2% chlorhexidine gel (CHX) at various time intervals on Enterococcus faecalis (E.f) when used as an intracanal medicament (ICM). Materials and Methods: For the in vitro study, 45 single-rooted teeth were used. After instrumentation, roots were infected with E.f and then divided into three groups (gps) (15 n/gp) according to the time interval for the medicament to be left inside the canal (1 week, 2 weeks and 3 weeks). ICM used was 2% CHX combined with CH (CH + CHX). At the end of each time interval, the antibacterial effect was evaluated using the agar diffusion test. For the in vivo study, 45 single-rooted teeth were selected. After sterilisation and access opening, the first pre-treatment sample was taken, then after instrumentation second post-instrumentation sample was obtained. Later, teeth were divided into 3 gps (15 n/gp) (1 week, 2 weeks and 3 weeks) according to the time interval for the medicament to be left inside the canal. ICM used was 2% CH + CHX. After each period, the third post-medication sample was taken. ANOVA and Tukey post hoc tests were used for statistical analysis. Results: Both in vitro and in vivo studies have found that 2% of CH + CHX had a significant antibacterial effect for 1 week and 2 weeks. However, the antibacterial effect was significantly decreased after 3 weeks. Conclusions: CH + CHX can be used successfully for the reduction of E.f for 14 days when used as ICM. |
| first_indexed | 2024-12-18T00:51:36Z |
| format | Article |
| id | doaj.art-0b951845c5e44545901fea9bebdae5b5 |
| institution | Directory Open Access Journal |
| issn | 0970-9290 1998-3603 |
| language | English |
| last_indexed | 2024-12-18T00:51:36Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dental Research |
| spelling | doaj.art-0b951845c5e44545901fea9bebdae5b52022-12-21T21:26:39ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032020-01-0131684685110.4103/ijdr.IJDR_359_19Residual antibacterial effect of calcium hydroxide combined with chlorhexidine gel as an intracanal medicamentNawal A Al-SabawiFatima A MohammadNjwan F ShehabIntroduction: Bacterial elimination from the root canal system is considered as an essential factor for a successful endodontic treatment. Aims: To investigate both in vitro and in vivo efficacy of calcium hydroxide paste (CH) combined with 2% chlorhexidine gel (CHX) at various time intervals on Enterococcus faecalis (E.f) when used as an intracanal medicament (ICM). Materials and Methods: For the in vitro study, 45 single-rooted teeth were used. After instrumentation, roots were infected with E.f and then divided into three groups (gps) (15 n/gp) according to the time interval for the medicament to be left inside the canal (1 week, 2 weeks and 3 weeks). ICM used was 2% CHX combined with CH (CH + CHX). At the end of each time interval, the antibacterial effect was evaluated using the agar diffusion test. For the in vivo study, 45 single-rooted teeth were selected. After sterilisation and access opening, the first pre-treatment sample was taken, then after instrumentation second post-instrumentation sample was obtained. Later, teeth were divided into 3 gps (15 n/gp) (1 week, 2 weeks and 3 weeks) according to the time interval for the medicament to be left inside the canal. ICM used was 2% CH + CHX. After each period, the third post-medication sample was taken. ANOVA and Tukey post hoc tests were used for statistical analysis. Results: Both in vitro and in vivo studies have found that 2% of CH + CHX had a significant antibacterial effect for 1 week and 2 weeks. However, the antibacterial effect was significantly decreased after 3 weeks. Conclusions: CH + CHX can be used successfully for the reduction of E.f for 14 days when used as ICM.http://www.ijdr.in/article.asp?issn=0970-9290;year=2020;volume=31;issue=6;spage=846;epage=851;aulast=Al-Sabawiantibacterialcalcium hydroxidechlorhexidineenterococcus faecalisintracanal medicament |
| spellingShingle | Nawal A Al-Sabawi Fatima A Mohammad Njwan F Shehab Residual antibacterial effect of calcium hydroxide combined with chlorhexidine gel as an intracanal medicament Indian Journal of Dental Research antibacterial calcium hydroxide chlorhexidine enterococcus faecalis intracanal medicament |
| title | Residual antibacterial effect of calcium hydroxide combined with chlorhexidine gel as an intracanal medicament |
| title_full | Residual antibacterial effect of calcium hydroxide combined with chlorhexidine gel as an intracanal medicament |
| title_fullStr | Residual antibacterial effect of calcium hydroxide combined with chlorhexidine gel as an intracanal medicament |
| title_full_unstemmed | Residual antibacterial effect of calcium hydroxide combined with chlorhexidine gel as an intracanal medicament |
| title_short | Residual antibacterial effect of calcium hydroxide combined with chlorhexidine gel as an intracanal medicament |
| title_sort | residual antibacterial effect of calcium hydroxide combined with chlorhexidine gel as an intracanal medicament |
| topic | antibacterial calcium hydroxide chlorhexidine enterococcus faecalis intracanal medicament |
| url | http://www.ijdr.in/article.asp?issn=0970-9290;year=2020;volume=31;issue=6;spage=846;epage=851;aulast=Al-Sabawi |
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