Prescribing pattern of anti-psychotic medications in patients with dementia in Oman: a retrospective observational study
Abstract Background Aggression, agitation, psychosis, and sleep disturbances are common behavioral symptoms of people with dementia and they can be distressing for both individuals and their carers. Due to their potential side effects, antipsychotic medications are recommended only for severe behavi...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-01-01
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| Series: | Middle East Current Psychiatry |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43045-022-00275-0 |
| _version_ | 1828069720627085312 |
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| author | Zainab Al-Rashdi Tamadhir Al-Mahrouqi Siham Al-Shamli Sathiya Panchatcharam Fatema Al-Busaidi Reem Al-Afani Naser Al-Balushi Hamed Al-Sinawi |
| author_facet | Zainab Al-Rashdi Tamadhir Al-Mahrouqi Siham Al-Shamli Sathiya Panchatcharam Fatema Al-Busaidi Reem Al-Afani Naser Al-Balushi Hamed Al-Sinawi |
| author_sort | Zainab Al-Rashdi |
| collection | DOAJ |
| description | Abstract Background Aggression, agitation, psychosis, and sleep disturbances are common behavioral symptoms of people with dementia and they can be distressing for both individuals and their carers. Due to their potential side effects, antipsychotic medications are recommended only for severe behavioral and psychological symptoms of dementia (BPSD). This study explores the prevalence, patterns, and associated factors with antipsychotic drug use among patients with dementia attending geriatric psychiatry services at Sultan Qaboos University Hospital (SQUH). Using a retrospective cross-sectional design, this study examines antipsychotic use among elderly patients aged 60 years or older with dementia who attended geriatric psychiatry services from January 2020 to December 2021. The following information was solicited: socio-demographic factors, type and severity of dementia, presence of co-morbid medical or mental illness, the psychotropic medications prescribed, the anti-psychotic medication use, duration of use, and the indication of use were solicited as well. A multivariate logistic regression analysis was conducted. Results The total prevalence of anti-psychotic use among elderly patients with dementia was 56.6%, and among them, 59% were prescribed anti-psychotics for more than 2 years. Being female, having non-Alzheimer’s dementia, experiencing severe stages of dementia, and having other medical or mental co-morbid conditions were independent predictors of antipsychotic drug use (odds ratio [OR] =1.85, confidence interval [CI] =1.04–3.30; OR=2.77, C.I. 1.52–5.04; OR=4.47, C.I. 2.18–9.18; and OR=2.54, C.I. 1.11–5.78, respectively). Conclusions Antipsychotic medication use is prevalent among elderly patients with dementia in Oman. The results from this study will help the policymakers and psychiatrists in Oman to plan for the use of non-pharmacological strategies as the first line of management for BPSD. |
| first_indexed | 2024-04-11T00:24:41Z |
| format | Article |
| id | doaj.art-0b96ac74e3854de789fc7e4671dbacc7 |
| institution | Directory Open Access Journal |
| issn | 2090-5416 |
| language | English |
| last_indexed | 2024-04-11T00:24:41Z |
| publishDate | 2023-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Middle East Current Psychiatry |
| spelling | doaj.art-0b96ac74e3854de789fc7e4671dbacc72023-01-08T12:03:53ZengSpringerOpenMiddle East Current Psychiatry2090-54162023-01-013011710.1186/s43045-022-00275-0Prescribing pattern of anti-psychotic medications in patients with dementia in Oman: a retrospective observational studyZainab Al-Rashdi0Tamadhir Al-Mahrouqi1Siham Al-Shamli2Sathiya Panchatcharam3Fatema Al-Busaidi4Reem Al-Afani5Naser Al-Balushi6Hamed Al-Sinawi7Psychiatry Residency Training Program, Oman Medical Speciality BoardPsychiatry Residency Training Program, Oman Medical Speciality BoardMinistry of HealthResearch and Studies Department, Oman Medical Specialty BoardMedical Internship Training Program, Sultan Qaboos University HospitalMedical Internship Training Program, Sultan Qaboos University HospitalBehavioural Medicine Department, Sultan Qaboos University HospitalBehavioural Medicine Department, Sultan Qaboos University HospitalAbstract Background Aggression, agitation, psychosis, and sleep disturbances are common behavioral symptoms of people with dementia and they can be distressing for both individuals and their carers. Due to their potential side effects, antipsychotic medications are recommended only for severe behavioral and psychological symptoms of dementia (BPSD). This study explores the prevalence, patterns, and associated factors with antipsychotic drug use among patients with dementia attending geriatric psychiatry services at Sultan Qaboos University Hospital (SQUH). Using a retrospective cross-sectional design, this study examines antipsychotic use among elderly patients aged 60 years or older with dementia who attended geriatric psychiatry services from January 2020 to December 2021. The following information was solicited: socio-demographic factors, type and severity of dementia, presence of co-morbid medical or mental illness, the psychotropic medications prescribed, the anti-psychotic medication use, duration of use, and the indication of use were solicited as well. A multivariate logistic regression analysis was conducted. Results The total prevalence of anti-psychotic use among elderly patients with dementia was 56.6%, and among them, 59% were prescribed anti-psychotics for more than 2 years. Being female, having non-Alzheimer’s dementia, experiencing severe stages of dementia, and having other medical or mental co-morbid conditions were independent predictors of antipsychotic drug use (odds ratio [OR] =1.85, confidence interval [CI] =1.04–3.30; OR=2.77, C.I. 1.52–5.04; OR=4.47, C.I. 2.18–9.18; and OR=2.54, C.I. 1.11–5.78, respectively). Conclusions Antipsychotic medication use is prevalent among elderly patients with dementia in Oman. The results from this study will help the policymakers and psychiatrists in Oman to plan for the use of non-pharmacological strategies as the first line of management for BPSD.https://doi.org/10.1186/s43045-022-00275-0AntipsychoticsDementiaBehavioral symptomsNeuropsychiatric SymptomsOman |
| spellingShingle | Zainab Al-Rashdi Tamadhir Al-Mahrouqi Siham Al-Shamli Sathiya Panchatcharam Fatema Al-Busaidi Reem Al-Afani Naser Al-Balushi Hamed Al-Sinawi Prescribing pattern of anti-psychotic medications in patients with dementia in Oman: a retrospective observational study Middle East Current Psychiatry Antipsychotics Dementia Behavioral symptoms Neuropsychiatric Symptoms Oman |
| title | Prescribing pattern of anti-psychotic medications in patients with dementia in Oman: a retrospective observational study |
| title_full | Prescribing pattern of anti-psychotic medications in patients with dementia in Oman: a retrospective observational study |
| title_fullStr | Prescribing pattern of anti-psychotic medications in patients with dementia in Oman: a retrospective observational study |
| title_full_unstemmed | Prescribing pattern of anti-psychotic medications in patients with dementia in Oman: a retrospective observational study |
| title_short | Prescribing pattern of anti-psychotic medications in patients with dementia in Oman: a retrospective observational study |
| title_sort | prescribing pattern of anti psychotic medications in patients with dementia in oman a retrospective observational study |
| topic | Antipsychotics Dementia Behavioral symptoms Neuropsychiatric Symptoms Oman |
| url | https://doi.org/10.1186/s43045-022-00275-0 |
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