DIAGNOSTICS AND TREATMENT OF EXCRETORY DEFICIENCY OF PANCREAS IN CHILDREN

<em>Excretory pancreatic insufficiency is relatively frequent pathology in pediatric and therapeutic practice. It can be divided to primary and secondary, inborn and acquired, absolute and relative one. The causes of primary pancreatic insufficiency are agenesia or hypoplasia of pancreas, cyst...

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Main Authors: S.V. Bel’mer, T.V. Gasilina
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2009-01-01
Series:Вопросы современной педиатрии
Online Access:http://vsp.spr-journal.ru:80/jour/article/view/1102
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author S.V. Bel’mer
T.V. Gasilina
author_facet S.V. Bel’mer
T.V. Gasilina
author_sort S.V. Bel’mer
collection DOAJ
description <em>Excretory pancreatic insufficiency is relatively frequent pathology in pediatric and therapeutic practice. It can be divided to primary and secondary, inborn and acquired, absolute and relative one. The causes of primary pancreatic insufficiency are agenesia or hypoplasia of pancreas, cystic fibrosis, Shwachman–Diamond syndrome. Secondary excretory pancreatic insufficiency can be caused by resection of pancreas, pancreatitis, pathology of mucous tunic of small intestine, abnormality of antitrypsinactivation with enterokinase deficiency, inactivation of enzymes by acid of duodenal contents in the presence of gastric hyper secretion and others. Excretory pancreatic deficiency has determined clinical signs and can be relatively easily diagnosed by simple laboratory methods: coprogramm and detection of elastase 1 in stool. The ways of its correction are determined by causes of disease, but modern high-active pancreatic enzymes medications must be necessary component of treatment in all cases.</em><br /><strong><em>Key words: children, pancreatic insufficiency, celiac disease, pancreatic enzymes medications.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em><em>Voprosy sovremennoi pediatrii — </em></em></em>Current Pediatrics. 2009;8(2):<em>114-118</em>)</em></span>
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spelling doaj.art-0b9be6bd1b174a3a94f3d2a49e1fbc882023-09-02T13:59:29Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352009-01-01821141181103DIAGNOSTICS AND TREATMENT OF EXCRETORY DEFICIENCY OF PANCREAS IN CHILDRENS.V. Bel’mer0T.V. Gasilina1Russian State Medical University, MoscowRussian State Medical University, Moscow<em>Excretory pancreatic insufficiency is relatively frequent pathology in pediatric and therapeutic practice. It can be divided to primary and secondary, inborn and acquired, absolute and relative one. The causes of primary pancreatic insufficiency are agenesia or hypoplasia of pancreas, cystic fibrosis, Shwachman–Diamond syndrome. Secondary excretory pancreatic insufficiency can be caused by resection of pancreas, pancreatitis, pathology of mucous tunic of small intestine, abnormality of antitrypsinactivation with enterokinase deficiency, inactivation of enzymes by acid of duodenal contents in the presence of gastric hyper secretion and others. Excretory pancreatic deficiency has determined clinical signs and can be relatively easily diagnosed by simple laboratory methods: coprogramm and detection of elastase 1 in stool. The ways of its correction are determined by causes of disease, but modern high-active pancreatic enzymes medications must be necessary component of treatment in all cases.</em><br /><strong><em>Key words: children, pancreatic insufficiency, celiac disease, pancreatic enzymes medications.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em><em>Voprosy sovremennoi pediatrii — </em></em></em>Current Pediatrics. 2009;8(2):<em>114-118</em>)</em></span>http://vsp.spr-journal.ru:80/jour/article/view/1102
spellingShingle S.V. Bel’mer
T.V. Gasilina
DIAGNOSTICS AND TREATMENT OF EXCRETORY DEFICIENCY OF PANCREAS IN CHILDREN
Вопросы современной педиатрии
title DIAGNOSTICS AND TREATMENT OF EXCRETORY DEFICIENCY OF PANCREAS IN CHILDREN
title_full DIAGNOSTICS AND TREATMENT OF EXCRETORY DEFICIENCY OF PANCREAS IN CHILDREN
title_fullStr DIAGNOSTICS AND TREATMENT OF EXCRETORY DEFICIENCY OF PANCREAS IN CHILDREN
title_full_unstemmed DIAGNOSTICS AND TREATMENT OF EXCRETORY DEFICIENCY OF PANCREAS IN CHILDREN
title_short DIAGNOSTICS AND TREATMENT OF EXCRETORY DEFICIENCY OF PANCREAS IN CHILDREN
title_sort diagnostics and treatment of excretory deficiency of pancreas in children
url http://vsp.spr-journal.ru:80/jour/article/view/1102
work_keys_str_mv AT svbelmer diagnosticsandtreatmentofexcretorydeficiencyofpancreasinchildren
AT tvgasilina diagnosticsandtreatmentofexcretorydeficiencyofpancreasinchildren