Effects of Vitamin D on Fertility, Pregnancy and Polycystic Ovary Syndrome—A Review

Polycystic ovary syndrome (PCOS) is one of the most common endocrine reproductive disorders in women. Vitamin D deficiency is also quite common in this condition. The degree of vitamin D deficiency correlates with the severity of PCOS. Both male and female vitamin D levels play a role in fertility a...

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Bibliographic Details
Main Authors: Szabolcs Várbíró, István Takács, László Tűű, Katalin Nas, Réka Eszter Sziva, Judit Réka Hetthéssy, Marianna Török
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Nutrients
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Online Access:https://www.mdpi.com/2072-6643/14/8/1649
Description
Summary:Polycystic ovary syndrome (PCOS) is one of the most common endocrine reproductive disorders in women. Vitamin D deficiency is also quite common in this condition. The degree of vitamin D deficiency correlates with the severity of PCOS. Both male and female vitamin D levels play a role in fertility and affect the outcomes of in vitro fertilization (IVF). Moreover, fertility and IVF indicators are improved by vitamin D not only in healthy women but in those diagnosed with PCOS. Both vitamin D deficiency and PCOS increase pregnancy-related complications. Vitamin D supplementation and optimal vitamin D levels decrease both maternal and fetal risk for complications and adverse events. Furthermore, vitamin D supplementation may ameliorate or even prevent pregnancy-related reversible bone loss in mothers. This review emphasizes the roles of vitamin D deficiency and vitamin D supplementation and their correlation with PCOS regarding reproductive health.
ISSN:2072-6643